1-benzyl-3-diazo-5-chloro-2-oxoindole

Base Information

• Chemical Name: 1-benzyl-3-diazo-5-chloro-2-oxoindole
• CAS No.: 1382468-32-7
• Molecular Formula: C₁₅H₁₀ClN₃O
• Molecular Weight: 283.717
• Mol file: 1382468-32-7.mol

Synonyms:1-benzyl-3-diazo-5-chloro-2-oxoindole

Chemical Property of 1-benzyl-3-diazo-5-chloro-2-oxoindole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-benzyl-3-diazo-5-chloro-2-oxoindole

There total 3 articles about 1-benzyl-3-diazo-5-chloro-2-oxoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C22H18ClN3O3S → 1-benzyl-3-diazo-5-chloro-2-oxoindole (1382468-32-7)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1021/acs.orglett.8b03557

Reference yield:

5-chloro-3-diazo-1,3-dihydro-2H-indol-2-one (65951-19-1) + benzyl bromide (100-39-0) → 1-benzyl-3-diazo-5-chloro-2-oxoindole (1382468-32-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

DOI:10.1021/ol5010752

Reference yield:

1-benzyl-5-chloroisatin (26960-68-9) → 1-benzyl-3-diazo-5-chloro-2-oxoindole (1382468-32-7)

Guidance literature:

1-benzyl-5-chloroisatin; With toluene-4-sulfonic acid hydrazide; In tetrahydrofuran; for 2h; Reflux;

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1002/anie.201804080

upstream raw materials:

5-chloro-3-diazo-1,3-dihydro-2H-indol-2-one

benzyl bromide

1-benzyl-5-chloroisatin

Downstream raw materials:

1-benzyl-5-chloro-3-hydroxy-3-(hydroxymethyl)indolin-2-one

1-benzyl-5-chloro-3-p-tolylindolin-2-one