Technology Process of (1-benzyl-1H-tetrazol-5-yl)diphenylmethanol
There total 3 articles about (1-benzyl-1H-tetrazol-5-yl)diphenylmethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
benzophenone; 1-benzyl-5-bromo-1H-tetrazole;
With
2-mesitylmagnesium bromide;
In
tetrahydrofuran;
at -20 - 20 ℃;
for 16h;
Inert atmosphere;
With
acetic acid;
In
tetrahydrofuran; tert-butyl methyl ether; water;
Inert atmosphere;
DOI:10.1055/s-0032-1316737
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium azide; acetic acid / 17 h / 80 °C
2.1: acetic acid; N-Bromosuccinimide / 6 h / 80 °C
3.1: 2-mesitylmagnesium bromide / tetrahydrofuran / 16 h / -20 - 20 °C / Inert atmosphere
3.2: Inert atmosphere
With
N-Bromosuccinimide; sodium azide; acetic acid; 2-mesitylmagnesium bromide;
In
tetrahydrofuran;
DOI:10.1055/s-0032-1316737
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid; N-Bromosuccinimide / 6 h / 80 °C
2.1: 2-mesitylmagnesium bromide / tetrahydrofuran / 16 h / -20 - 20 °C / Inert atmosphere
2.2: Inert atmosphere
With
N-Bromosuccinimide; acetic acid; 2-mesitylmagnesium bromide;
In
tetrahydrofuran;
DOI:10.1055/s-0032-1316737
