2,2',4,4',5,5'-hexamethoxybiphenyl

Base Information

• Chemical Name: 2,2',4,4',5,5'-hexamethoxybiphenyl
• CAS No.: 1702-67-6
• Molecular Formula: C₁₈H₂₂O₆
• Molecular Weight: 334.369
• Mol file: 1702-67-6.mol

Synonyms:2,2',4,4',5,5'-hexamethoxybiphenyl

Chemical Property of 2,2',4,4',5,5'-hexamethoxybiphenyl

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2,2',4,4',5,5'-HEXAMETHOXYBIPHENYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2',4,4',5,5'-hexamethoxybiphenyl

There total 50 articles about 2,2',4,4',5,5'-hexamethoxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-iodo-2,4,5-trimethoxybenzene (23149-33-9) → 2,2',4,4',5,5'-hexamethoxybiphenyl (1702-67-6)

Guidance literature:

With boron trifluoride diethyl etherate;

DOI:10.1016/0040-4020(96)00134-2

Reference yield: 99.0%

bis(2,3,5-trimethoxyphenyl)selenium → 2,2',4,4',5,5'-hexamethoxybiphenyl (1702-67-6)

Guidance literature:

With molybdenum(V) chloride; In dichloromethane; water; at 22 ℃; for 0.333333h;

Reference yield: 98.0%

1,2,4-trimethoxy-benzene (135-77-3) → 2,2',4,4',5,5'-hexamethoxybiphenyl (1702-67-6)

Guidance literature:

With molybdenum(V) chloride; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1055/s-2002-22708

upstream raw materials:

tetrachloromethane

formic acid

1-iodo-2,4,5-trimethoxybenzene

1,2,4-trimethoxy-benzene

Downstream raw materials:

2,3,6,7-tetrahydroxydibenzofuran

Refernces

• 1、 Wirtanen, Tom,Aikonen, Santeri,Muuronen, Mikko,Melchionna, Michele,Kemell, Marianna,Davodi, Fatemeh,Kallio, Tanja,Hu, Tao,Helaja, Juho. "Carbocatalytic Oxidative Dehydrogenative Couplings of (Hetero)Aryls by Oxidized Multi-Walled Carbon Nanotubes in Liquid Phase". . p. 12288 - 12293. Retrieved 2019.
• 2、 Eisenhofer, Anna,Wille, Uta,K?nig, Burkhard. "Nitrosonium-Mediated Phenol-Arene Cross-Coupling Involving Direct C-H Activation". . p. 407 - 412. Retrieved 2017.
• 3、 Beil, Sebastian B.,Bomm, Alexander,Breiner, Manuel,Holtkamp, Michael,Karst, Uwe,Müller, Timo,Schüll, Aaron,Schade, Wolfgang,Schollmeyer, Dieter,Schulz, Lara,Waldvogel, Siegfried R.. "About the selectivity and reactivity of active nickel electrodes in C-C coupling reactions". . p. 14249 - 14253. Retrieved 2020/04/23.
• 4、 Beil, Sebastian B.,Uecker, Ise,Franzmann, Peter,Müller, Timo,Waldvogel, Siegfried R.. "Mild, Fast, and Easy to Conduct MoCl5-Mediated Dehydrogenative Coupling Reactions in Flow". supporting information. p. 4107 - 4110. Retrieved 2018/07/15.