r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene

Base Information

• Chemical Name: r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene
• CAS No.: 83731-35-5
• Molecular Formula: C₂₂H₂₀O₄
• Molecular Weight: 348.398
• Mol file: 83731-35-5.mol

Synonyms:r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene

Chemical Property of r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene

There total 1 articles about r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

rac-anti-naphthalene 1,2:3,4-dioxide (58717-74-1) + phenol (108-95-2,27073-41-2) → r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene (83731-35-5)

Guidance literature:

With sodium hydroxide; In acetonitrile; for 24h; Heating;

DOI:10.1021/jo00148a021

Reference yield: 86.0%

r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene (83731-35-5) + methanesulfonyl chloride (124-63-0) → Methanesulfonic acid (1S,2R,3R,4S)-3-methanesulfonyloxy-1,4-diphenoxy-1,2,3,4-tetrahydro-naphthalen-2-yl ester (83731-36-6)

Guidance literature:

With pyridine; for 72h; Ambient temperature;

DOI:10.1021/jo00148a021

Reference yield: 81.0%

r,t-1,4-diphenoxy-t,c-2,3-dihydroxy-1,2,3,4-tetrahydronaphthalene (83731-35-5) + 2,2-dimethoxy-propane (77-76-9) → r,t-1,4-diphenoxy-t,c-2,3-O-isopropylidene-1,2,3,4-tetrahydronaphthalene (83731-37-7)

Guidance literature:

With toluene-4-sulfonic acid; Ambient temperature;

DOI:10.1021/jo00148a021

upstream raw materials:

rac-anti-naphthalene 1,2:3,4-dioxide

phenol

Downstream raw materials:

Methanesulfonic acid (1S,2R,3R,4S)-3-methanesulfonyloxy-1,4-diphenoxy-1,2,3,4-tetrahydro-naphthalen-2-yl ester

r,t-1,4-diphenoxy-t,c-2,3-O-isopropylidene-1,2,3,4-tetrahydronaphthalene

1,4-diphenoxynaphthalene