2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate

Base Information

• Chemical Name: 2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate
• CAS No.: 1006904-71-7
• Molecular Formula: CF₃O*C₇H₁₆N₃
• Molecular Weight: 227.23
• Mol file: 1006904-71-7.mol

Synonyms:2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate

Chemical Property of 2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate

There total 1 articles about 2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-dimethylamino-1,3-dimethylimidazolinium difluorotrimethylsilicate (479024-67-4) + trifluoromethyl trifluoromethanesulfonate (3582-05-6) → 2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate (1006904-71-7) + Trifluoromethanesulfonyl fluoride (335-05-7)

Guidance literature:

In acetonitrile; at -30 - 20 ℃;

DOI:10.1016/j.tetlet.2007.11.105

Reference yield: 91.0%

2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate (1006904-71-7) + 2-(1,3-dioxoisoindolin-2-yl)ethyl trifluoromethanesulfonate (127175-39-7) → N-[2-(trifluoromethoxy)ethyl]phthalimide (329710-82-9)

Guidance literature:

In acetonitrile; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2007.11.105

Reference yield: 57.0%

2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate (1006904-71-7) + trifluoromethylsulfonic anhydride (358-23-6) + hydroxy-phenyl-acetic acid ethyl ester (774-40-3,4358-88-7) → ethyl 2-phenyl-2-(trifluoromethoxy)acetate (1006904-69-3) + fluoro-phenyl-acetic acid ethyl ester (643-77-6)

Guidance literature:

trifluoromethylsulfonic anhydride; hydroxy-phenyl-acetic acid ethyl ester; In dichloromethane; at -78 ℃;

2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate; With 2,4,6-trimethyl-pyridine; In acetonitrile; at -78 - 20 ℃; for 6h; Further stages.;

DOI:10.1016/j.tetlet.2007.11.105

upstream raw materials:

2-dimethylamino-1,3-dimethylimidazolinium difluorotrimethylsilicate

trifluoromethyl trifluoromethanesulfonate

Downstream raw materials:

ethyl 2-phenyl-2-(trifluoromethoxy)acetate

fluoro-phenyl-acetic acid ethyl ester

fluorobenzene

1-trifluoromethoxybenzene