14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.04,6]nonadec-7-ene-4-carboxyric acid

Base Information

Chemical Name:14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid
CAS No.:1044559-34-3
Molecular Formula:C₃₆H₄₁N₅O₇
Molecular Weight:655.751
Hs Code.:

Synonyms:14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

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Chemical Property of 14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

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Technology Process of 14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

There total 1 articles about 14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1044559-31-0
14-(4-methoxy-benzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxylic acid ethyl ester

: 1044559-34-3
14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

Guidance literature:: 14-(4-methoxy-benzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxylic acid ethyl ester; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With citric acid; In tetrahydrofuran; methanol; water;

Reference yield:

: 154350-29-5
cyclopropanesulphonamide

: 1044559-34-3
14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

: 1044559-37-6
cyclopropanesulfonic acid [14-(4-methoxybenzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carbonyl]amide

Guidance literature:: 14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.5h;

cyclopropanesulphonamide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 72h;

Reference yield:

: 669008-26-8
1-methylcyclopropane-1-sulfonamide

: 1044559-34-3
14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid

: 1044559-71-8
1-methyl-cyclopropanesulfonic acid [14-(4-methoxy-benzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carbonyl]-amide

Guidance literature:: 14-(4-methoxybenzyl)-18-(2-methoxy-6-phenylpyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxyric acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 2.5h;

1-methylcyclopropane-1-sulfonamide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃;