Edaravone trimer

Base Information

Chemical Name:Edaravone trimer
CAS No.:68195-63-1
Molecular Formula:C₃₀H₂₆N₆O₃
Molecular Weight:518.575
Hs Code.:
UNII:QD3GWF6HFZ
Nikkaji Number:J1.990.579I
Mol file:68195-63-1.mol

Synonyms:68195-63-1;EDARAVONE TRIMER;5-methyl-4,4-bis(3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-yl)-2-phenylpyrazol-3-one;3,3'',5'-TRIMETHYL-1,1'',2'-TRIPHENYL-1H,1''H-[4,4':4',4''-TERPYRAZOLE]-3',5,5''(2'H,4H,4''H)-TRIONE;[4,4':4',4''-Ter-4H-pyrazole]-3,3',3''(2H,2'H,2''H)-trione,5,5',5''-trimethyl-2,2',2''-triphenyl-;QD3GWF6HFZ;AO-790/15416001;F19276;A899886;[4,4'-4',4''-Ter-2-pyrazoline]-5,5',5''-trione, 3,3',3''-trimethyl-1,1',1''-triphenyl-;[4,4':4',4''-Ter-4H-pyrazole]-3,3',3''(2H,2'H,2''H)-trione, 5,5',5''-trimethyl-2,2',2''-triphenyl-;5,5',5''-Trimethyl-2,2',2''-triphenyl-2,2'',4,4''-tetrahydro-3H,3''H-[4,4':4',4''-terpyrazole]-3,3',3''(2'H)-trione

Suppliers and Price of Edaravone trimer

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Edaravone trimer

Chemical Property:

Melting Point:200 °C (decomp)(Solv: ethanol (64-17-5))
Boiling Point:770.6±60.0 °C(Predicted)
PKA:2.15±0.70(Predicted)
Density:1.34±0.1 g/cm3(Predicted)
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:518.20663871
Heavy Atom Count:39
Complexity:1050

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=O)C1C2(C(=NN(C2=O)C3=CC=CC=C3)C)C4C(=NN(C4=O)C5=CC=CC=C5)C)C6=CC=CC=C6
Uses Edaravone Trimer is an impurity of Edaravone ( ). Edaravone is an intravenous medication used to help with recovery following a stroke and to treat amyotrophic lateral sclerosis.

Technology Process of Edaravone trimer

There total 6 articles about Edaravone trimer which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 19735-89-8
3-methyl-1-phenylpyrazolin-5(4H)-one

: 74451-57-3
(E)-5,5'-dimethyl-2,2'-diphenyl-2H,2'H-[4,4']bipyrazolylidene-3,3'-dione

: 68195-63-1
4,4-Bis-(3-methyl-phenyl-pyrazolin-5-on-4-yl)-3-methyl-1-phenyl-pyrazolin-5-on

Guidance literature:: In benzene; at 25 ℃;
DOI:10.1002/prac.19933350706

Reference yield: 81.0%

: 19735-89-8
3-methyl-1-phenylpyrazolin-5(4H)-one

: 68195-63-1
4,4-Bis-(3-methyl-phenyl-pyrazolin-5-on-4-yl)-3-methyl-1-phenyl-pyrazolin-5-on

Guidance literature:: With 4-cyano-2,6-di-t-butylphenoxyl radical; In benzene; at 25 ℃;
DOI:10.1002/prac.19933350706

Reference yield: 80.0%

: 89-25-8
edaravone

: 68195-63-1
4,4-Bis-(3-methyl-phenyl-pyrazolin-5-on-4-yl)-3-methyl-1-phenyl-pyrazolin-5-on

Guidance literature:: With Trametes versicolor laccase; In aq. phosphate buffer; at 20 ℃; for 4h; pH=4; Time; Solvent;
DOI:10.1007/s12039-021-01943-0