4-NITROPHENOL

Base Information

• Chemical Name: 4-NITROPHENOL
• CAS No.: 89830-32-0
• Molecular Formula: C₆H₅NO₃
• Molecular Weight: 139.111
• Mol file: 89830-32-0.mol

Synonyms:4-NITROPHENOL

Chemical Property of 4-NITROPHENOL

Chemical Property:

• PKA: 7.15(at 25℃)
• PSA: 66.05000
• LogP: 1.82360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITROPHENOL

There total 2476 articles about 4-NITROPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C42H65NO33 (74173-30-1,140694-63-9) → p-nitrophenyl-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranoside (3482-57-3,4419-94-7,7344-00-5,17400-77-0,56846-39-0,78248-67-6,80446-81-7) + 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 4-nitrophenyl α-maltotrioside (66451-58-9) + 4-nitrophenyl α-maltotetraoside (66068-37-9) + p‐nitrophenyl‐α‐D-maltopentoglycoside (66068-38-0) + 4-nitrophenyl-α-D-glucopyranoside (3767-28-0)

Guidance literature:

In water; at 35 ℃; Rate constant; Product distribution; acetate buffer pH 5.5, barley alpha-amylase 1 or 2;

DOI:10.1016/0008-6215(92)85080-J

Reference yield:

p-nitrophenolate (14609-74-6) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0)

Guidance literature:

With triethylamine; In dimethyl sulfoxide; benzene; at 25 ℃; Equilibrium constant; ionization in solvent mixtures with different ratio;

DOI:10.1021/j100463a022

Reference yield:

4-nitrobenzenediazonium tetrafluoroborate (456-27-9) + 4-nitro-benzenediazohydroxide, sodium salt (32352-96-8) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + nitrobenzene (98-95-3,26969-40-4)

Guidance literature:

In acetonitrile; Product distribution; Mechanism;

upstream raw materials:

pyridine

tetranitromethane

phenol

methanol

Downstream raw materials:

4-nitro-2-(piperidin-1'-ylmethyl)phenol

2-((4-nitrophenoxy)methyl)benzothiazole

bis(4-nitrophenoxy)methane

N-(2-hydroxy-5-nitro-benzyl)-phthalimide

Refernces

• 1、 Nejatie, Ali,Colombo, Cinzia,Hakak-Zargar, Benyamin,Bennet, Andrew J.. "A Mechanistic Study on the Non-enzymatic Hydrolysis of Kdn Glycosides". . . Retrieved 2022/01/13.
• 2、 -. "Synthetic method of p-hydroxybenzonitrile". Paragraph 0032-0034. . Retrieved 2021/01/30.