(2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate

Base Information

• Chemical Name: (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate
• CAS No.: 1118765-36-8
• Molecular Formula: C₂₈H₃₀O₈
• Molecular Weight: 494.541
• Mol file: 1118765-36-8.mol

Synonyms:(2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate

Chemical Property of (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate

There total 1 articles about (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.4%

4',4''-O,O-dimethylcurcumin (160096-59-3) + propynoic acid ethyl ester (623-47-2) → (2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate (1118765-36-8)

Guidance literature:

4',4''-O,O-dimethylcurcumin; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h;

propynoic acid ethyl ester; In tetrahydrofuran; mineral oil; at 20 ℃; for 24.1667h;

DOI:10.1016/j.bmc.2008.10.057

Reference yield: 76.0%

(2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate (1118765-36-8) → ethyl (E,E,E)-3-(3,5-bis(3,4-dimethoxystyryl)-1H-pyrazol-4-yl)acrylate (1118765-43-7)

Guidance literature:

With hydrazine hydrochloride; acetic acid; In ethanol; for 40h; Reflux;

DOI:10.1016/j.bmc.2008.10.057

Reference yield: 66.0%

(2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate (1118765-36-8) → (1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4-((E)-3-hydroxyprop-1-enyl)hepta-1,6-diene-3,5-dione (1118765-38-0)

Guidance literature:

(2E,6E)-ethyl-7-(3,4-dimethoxyphenyl)-4-((E)-3-(3,4-dimethoxyphenyl)acryloyl)-5-oxohepta-2,6-dienoate; With diisobutylaluminium hydride; In dichloromethane; at -78 - 20 ℃; for 2h;

With water; rochelle salt; In dichloromethane;

DOI:10.1016/j.bmc.2008.10.057

upstream raw materials:

4',4''-O,O-dimethylcurcumin

propynoic acid ethyl ester

Downstream raw materials:

(1E,6E)-1,7-bis(3,4-dimethoxyphenyl)-4-((E)-3-hydroxyprop-1-enyl)hepta-1,6-diene-3,5-dione

ethyl (E,E,E)-3-(3,5-bis(3,4-dimethoxystyryl)-1H-pyrazol-4-yl)acrylate