C₁₇H₁₀ClF₃O₅S

Base Information

• Chemical Name: C₁₇H₁₀ClF₃O₅S
• CAS No.: 1369830-93-2
• Molecular Formula: C₁₇H₁₀ClF₃O₅S
• Molecular Weight: 418.778
• Mol file: 1369830-93-2.mol

Synonyms:C₁₇H₁₀ClF₃O₅S

Chemical Property of C₁₇H₁₀ClF₃O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₀ClF₃O₅S

There total 3 articles about C₁₇H₁₀ClF₃O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

trifluoromethanesulfonic acid 4-methyl-2-oxo-5-trifluoromethanesulfonyloxy-2H-chromen-7-yl ester (1369830-68-1) + 4-Chlorophenylboronic acid (1679-18-1) → C17H10ClF3O5S (1369830-93-2)

Guidance literature:

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 70 ℃; for 8h;

DOI:10.1055/s-0031-1290072

Reference yield:

3,5-dihydroxyphenol (108-73-6) → C17H10ClF3O5S (1369830-93-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: polyphosphoric acid

2.1: triethylamine / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

2.2: 6 h / -78 - 20 °C / Inert atmosphere

3.1: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 8 h / 70 °C

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In dichloromethane; toluene; 1.1: Pechmann condensation / 3.1: Suzuki coupling;

DOI:10.1055/s-0031-1290072

Reference yield:

4-methyl-5,7-dihydroxycoumarin (2107-76-8) → C17H10ClF3O5S (1369830-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

1.2: 6 h / -78 - 20 °C / Inert atmosphere

2.1: potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 8 h / 70 °C

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In dichloromethane; toluene; 2.1: Suzuki coupling;

DOI:10.1055/s-0031-1290072

upstream raw materials:

trifluoromethanesulfonic acid 4-methyl-2-oxo-5-trifluoromethanesulfonyloxy-2H-chromen-7-yl ester

4-Chlorophenylboronic acid

3,5-dihydroxyphenol

4-methyl-5,7-dihydroxycoumarin