2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

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Chemical Name:2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine
CAS No.:1605289-06-2
Molecular Formula:C₂₀H₁₆FN₃S₂
Molecular Weight:381.498
Hs Code.:

Synonyms:2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

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Technology Process of 2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

There total 2 articles about 2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1605289-01-7
6-(4-fluorophenyl)-4-imino-7-phenylpyrrolo[2,3-d][1,3]thiazin-2(1H,4H,7H)-thione

: 75-03-6
ethyl iodide

: 1605289-06-2
2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 24h;
DOI:10.1016/j.ejmech.2014.03.068

Reference yield:

: 748810-21-1
2-amino-5-(4-fluoro-phenyl)-1-phenyl-1H-pyrrole-3-carbonitrile

: 1605289-06-2
2-(ethylthio)-6-(4-fluorophenyl)-7-phenylpyrrolo[2,3-d][1,3]thiazin-4(7H)-imine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 3 h / Reflux

2: sodium hydride / N,N-dimethyl-formamide / 24 h

With pyridine; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2014.03.068