Technology Process of 2:3,7:8,12:13,17:18-tetrabutanoporphyrin
There total 9 articles about 2:3,7:8,12:13,17:18-tetrabutanoporphyrin which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4,5,6,7-tetrahydro-2H-isoindole; benzaldehyde;
In
dichloromethane;
at 20 ℃;
for 0.333333h;
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at 20 ℃;
for 4h;
With
2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
dichloromethane;
Further stages.;
DOI:10.1002/anie.200604240
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 90 percent / t-BuOK / tetrahydrofuran / 4 h / 20 °C
2.1: potassium hydroxide / ethane-1,2-diol / 1 h / Heating
3.1: CH2Cl2 / 0.17 h / 20 °C
3.2: BF3*OEt2 / CH2Cl2 / 2 h / 20 °C
3.3: 54 percent / DDQ / CH2Cl2
With
potassium hydroxide; potassium tert-butylate;
In
tetrahydrofuran; dichloromethane; ethylene glycol;
1.1: Barton-Zard reaction;
DOI:10.1021/jo0350054
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium hydroxide / ethane-1,2-diol / 1 h / Heating
2.1: CH2Cl2 / 0.17 h / 20 °C
2.2: BF3*OEt2 / CH2Cl2 / 2 h / 20 °C
2.3: 54 percent / DDQ / CH2Cl2
With
potassium hydroxide;
In
dichloromethane; ethylene glycol;
DOI:10.1021/jo0350054
