ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Base Information

Chemical Name:ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate
CAS No.:1356602-09-9
Molecular Formula:C₂₅H₂₅NO₅
Molecular Weight:419.477
Hs Code.:

Synonyms:ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Suppliers and Price of ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

There total 8 articles about ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1356602-06-6
ethyl (2E)-3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)prop-2-enoate

: 1356602-09-9
ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethyl acetate; at 20 ℃; for 3h;

Reference yield:

: 70-11-1
α-bromoacetophenone

: 1356602-09-9
ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / 2 h / 20 - 80 °C

2.1: phosphorus tribromide / dichloromethane / 1.08 h / 0 - 20 °C

2.2: 20 °C

3.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

3.2: 12 h / 20 - 80 °C

4.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C

4.2: 12 h / 0 - 20 °C

5.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 3 h / 20 °C

With hydrogen; phosphorus tribromide; sodium hydride; potassium carbonate; caesium carbonate; palladium 10% on activated carbon; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 623-05-2
(4-hydroxyphenyl)methanol

: 1356602-09-9
ethyl 3-(6-{[4-(2-oxo-2-phenylethoxy)benzyl]oxy}pyridin-3-yl)propanoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium carbonate / acetonitrile / 2 h / 20 - 80 °C

2.1: phosphorus tribromide / dichloromethane / 1.08 h / 0 - 20 °C

2.2: 20 °C

3.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

3.2: 12 h / 20 - 80 °C

4.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C

4.2: 12 h / 0 - 20 °C

5.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 3 h / 20 °C

With hydrogen; phosphorus tribromide; sodium hydride; potassium carbonate; caesium carbonate; palladium 10% on activated carbon; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;