(2R)-2-(2,5-difluorophenyl)pyrrolidine

Base Information

Chemical Name:(2R)-2-(2,5-difluorophenyl)pyrrolidine
CAS No.:1218935-59-1
Molecular Formula:C₁₀H₁₁F₂N
Molecular Weight:183.201
Hs Code.:
UNII:RPF7VP5RFX

Synonyms:(2R)-2-(2,5-difluorophenyl)pyrrolidine;1218935-59-1;(R)-2-(2,5-difluorophenyl)pyrrolidine;Pyrrolidine, 2-(2,5-difluorophenyl)-, (2R)-;RPF7VP5RFX;C10H11F2N;2-(2,5-Difluorophenyl)pyrrolidine, (R)-;MFCD07772701;UNII-RPF7VP5RFX;SCHEMBL932672;NCXSNNVYILYEBC-SNVBAGLBSA-N;AMY12406;AKOS015933481;AC-30674;DS-11702;CS-0055107;I11001

Suppliers and Price of (2R)-2-(2,5-difluorophenyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R)-2-(2,5-Difluorophenyl)pyrrolidine
1g
$ 560.00

Chemenu
(2R)-2-(2,5-Difluorophenyl)pyrrolidine 95%
1g
$ 407.00

American Custom Chemicals Corporation
(2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE 95.00%
0.25G
$ 326.00

Alichem
(R)-2-(2,5-Difluorophenyl)pyrrolidine
1g
$ 435.00

ACHEMBLOCK
(2R)-2-(2,5-difluorophenyl)pyrrolidine 95%
1G
$ 305.00

ACHEMBLOCK
(2R)-2-(2,5-difluorophenyl)pyrrolidine 95%
250MG
$ 115.00

Total 48 raw suppliers

Chemical Property of (2R)-2-(2,5-difluorophenyl)pyrrolidine

Chemical Property:

Boiling Point:213.5±40.0 °C(Predicted)
PKA:9.02±0.10(Predicted)
Density:1.164±0.06 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:183.08595568
Heavy Atom Count:13
Complexity:174

Purity/Quality:

99%, ^*data from raw suppliers

(2R)-2-(2,5-Difluorophenyl)pyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C2=C(C=CC(=C2)F)F
Isomeric SMILES:C1C[C@@H](NC1)C2=C(C=CC(=C2)F)F
Uses (2R)-2-(2,5-Difluorophenyl)pyrrolidine is used in the synthesis of imidazo[1,2-b]pyridazine compounds as inhibitors of Trk kinases.

Technology Process of (2R)-2-(2,5-difluorophenyl)pyrrolidine

There total 47 articles about (2R)-2-(2,5-difluorophenyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%