5-fluorobenzofuran-2-carboxylic Acid

Base Information

Chemical Name:5-fluorobenzofuran-2-carboxylic Acid
CAS No.:89197-62-6
Molecular Formula:C9H5FO3
Molecular Weight:180.1326
Hs Code.:2932999099
European Community (EC) Number:818-059-3
DSSTox Substance ID:DTXSID60450820
Wikidata:Q82270642
Mol file:89197-62-6.mol

Synonyms:5-fluorobenzofuran-2-carboxylic Acid;89197-62-6;5-FLUORO-1-BENZOFURAN-2-CARBOXYLIC ACID;MFCD09038172;2-Benzofurancarboxylicacid, 5-fluoro-;2-BENZOFURANCARBOXYLIC ACID, 5-FLUORO-;5-fluorobenzo[b]furan-2-carboxylic acid;SCHEMBL2897831;DTXSID60450820;HITUZQPFDWNUHA-UHFFFAOYSA-N;STL217538;AKOS000320415;MB06881;AS-44008;SY045635;CS-0062578;EN300-74251;5-FLUORO-1-BENZOFURAN-2-CARBOXYLICACID;W10186;A861279;AS-871/43474828;F2124-1204;Z979493270

Suppliers and Price of 5-fluorobenzofuran-2-carboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Fluoro-1-benzofuran-2-carboxylicAcid
50mg
$ 45.00

TRC
5-Fluoro-1-benzofuran-2-carboxylicAcid
100mg
$ 60.00

SynQuest Laboratories
5-Fluoro-1-benzofuran-2-carboxylicacid
250 mg
$ 45.00

SynQuest Laboratories
5-Fluoro-1-benzofuran-2-carboxylicacid
1 g
$ 135.00

SynQuest Laboratories
5-Fluoro-1-benzofuran-2-carboxylicacid
5 g
$ 480.00

Crysdot
5-Fluorobenzofuran-2-carboxylicacid 95+%
5g
$ 309.00

Chemenu
5-Fluorobenzofuran-2-carboxylicacid 95%
5g
$ 289.00

Apolloscientific
5-Fluoro-1-benzofuran-2-carboxylicacid
1g
$ 84.00

Apolloscientific
5-Fluoro-1-benzofuran-2-carboxylicacid
5g
$ 300.00

Apolloscientific
5-Fluoro-1-benzofuran-2-carboxylicacid
250mg
$ 28.00

Total 14 raw suppliers

Chemical Property of 5-fluorobenzofuran-2-carboxylic Acid

Chemical Property:

Boiling Point:317.012 °C at 760 mmHg
PKA:2.95±0.30(Predicted)
Flash Point:145.524 °C
PSA：50.44000
Density:1.463 g/cm³
LogP:2.27010
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:180.02227218
Heavy Atom Count:13
Complexity:219

Purity/Quality:

99%, ^*data from raw suppliers

5-Fluoro-1-benzofuran-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)C=C(O2)C(=O)O

Technology Process of 5-fluorobenzofuran-2-carboxylic Acid

There total 7 articles about 5-fluorobenzofuran-2-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 347-54-6
5-fluoro-2-hydroxybenzaldehyde

: 685-87-0
Diethyl 2-bromomalonate

: 89197-62-6
5-fluorobenzofuran-2-carboxylic acid

Guidance literature:: 5-fluoro-2-hydroxybenzaldehyde; Diethyl 2-bromomalonate; With tetrabutylammomium bromide; potassium carbonate; potassium iodide; In toluene; at 80 ℃; for 21h;

With potassium hydroxide; In ethanol; toluene; at 80 ℃; for 25h;

Reference yield: 87.0%

: 93849-31-1
ethyl 5-fluoro-1H-benzofuran-2-carboxylate

: 89197-62-6
5-fluorobenzofuran-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/jm0203433

Reference yield: 73.0%

: 91703-57-0
2-(2,2-dibromovinyl)-4-fluorophenol

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 89197-62-6
5-fluorobenzofuran-2-carboxylic acid

Guidance literature:: With [2,2]bipyridinyl; water; triethylamine; copper(ll) bromide; In tert-butyl alcohol; at 90 ℃; for 8h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.0c01620