5-Fluoro-2-hydroxybenzaldehyde

Base Information

Chemical Name:5-Fluoro-2-hydroxybenzaldehyde
CAS No.:347-54-6
Molecular Formula:C7H5FO2
Molecular Weight:140.114
Hs Code.:29130000
European Community (EC) Number:626-267-9
DSSTox Substance ID:DTXSID50371994
Nikkaji Number:J612.214K
Wikidata:Q72477016
Mol file:347-54-6.mol

Synonyms:5-fluorosalicylaldehyde;F-SA compound

Suppliers and Price of 5-Fluoro-2-hydroxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Fluoro-2-hydroxybenzaldehyde
50mg
$ 60.00

TCI Chemical
5-Fluorosalicylaldehyde >98.0%(GC)(T)
25g
$ 154.00

TCI Chemical
5-Fluorosalicylaldehyde >98.0%(GC)(T)
5g
$ 37.00

SynQuest Laboratories
5-Fluoro-2-hydroxybenzaldehyde 97%
100 g
$ 325.00

SynQuest Laboratories
5-Fluoro-2-hydroxybenzaldehyde 97%
5 g
$ 25.00

SynQuest Laboratories
5-Fluoro-2-hydroxybenzaldehyde 97%
25 g
$ 95.00

Sigma-Aldrich
5-Fluorosalicylaldehyde 97%
1g
$ 106.00

Medical Isotopes, Inc.
5-Fluoro-2-hydroxybenzaldehyde 98%
1 g
$ 309.00

Medical Isotopes, Inc.
5-Fluoro-2-hydroxybenzaldehyde 98%
100 g
$ 641.00

Matrix Scientific
5-Fluoro-2-hydroxybenzaldehyde 95+%
5g
$ 18.00

Total 95 raw suppliers

Chemical Property of 5-Fluoro-2-hydroxybenzaldehyde

Chemical Property:

Appearance/Colour:White crystal
Vapor Pressure:3.3mmHg at 25°C
Melting Point:82-85 °C
Refractive Index:1.531
Boiling Point:207.4°C at 760 mmHg
PKA:8.18±0.18(Predicted)
Flash Point:79.2 °C
PSA：37.30000
Density:1.35 g/cm³
LogP:1.34380
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Sensitive.:Air Sensitive
Solubility.:soluble in Methanol
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:140.02735756
Heavy Atom Count:10
Complexity:127

Purity/Quality:

99% ^*data from raw suppliers

5-Fluoro-2-hydroxybenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C=O)O
Uses 5-Fluorosalicylaldehyde may be used to synthesize:managanese (III) complex [MnLa(μ1,3-N3)]n [H2La = N,N′-bis(5-fluorosalicylidene)-1,2-diaminoethane]enantiopure 4-amino-6-fluoro-3-(hydroxymethyl)chromanes4,4′-difluoro-2,2′-[(hydrazine-1,2-diylidene)bis(methanylylidene)]-diphenolN,N′-bis(5-fluoro-2-hydroxybenzylidene)ethylenediamineN,N′-(2-hydroxypropane-1,3-diyl)-bis(salicylaldimine (H2L)

Technology Process of 5-Fluoro-2-hydroxybenzaldehyde

There total 15 articles about 5-Fluoro-2-hydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 371-41-5
4-Fluorophenol

: 347-54-6
5-fluoro-2-hydroxybenzaldehyde

Guidance literature:: formaldehyd; With triethylamine; magnesium chloride; In tetrahydrofuran; for 0.166667h; Inert atmosphere;

4-Fluorophenol; In tetrahydrofuran; at 75 ℃; regioselective reaction; Inert atmosphere;
DOI:10.15227/orgsyn.082.0064

Reference yield: 80.0%

: 347-54-6
5-fluoro-2-hydroxybenzaldehyde

Guidance literature:: With triethylamine; magnesium chloride; In acetonitrile; for 4h; Reflux;

Reference yield: 75.0%

: 452-72-2
4-fluoro-2-methylphenol

: 347-54-6
5-fluoro-2-hydroxybenzaldehyde

Guidance literature:: With C₁₅H₁₁ClN₄SZn; p-benzoquinone; In tert-butyl alcohol; for 8h; Reagent/catalyst;
DOI:10.1016/j.jphotochem.2021.113455