2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Base Information

Chemical Name:2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester
CAS No.:656809-49-3
Molecular Formula:C₁₆H₂₄O₆Si
Molecular Weight:340.448
Hs Code.:

Synonyms:2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Suppliers and Price of 2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

There total 4 articles about 2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 124-38-9,18923-20-1
carbon dioxide

: 656809-46-0
2,4-dimethoxy-6-methylbenzoic acid 2-trimethylsilanylethyl ester

: 656809-49-3
2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Guidance literature:: 2,4-dimethoxy-6-methylbenzoic acid 2-trimethylsilanylethyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.416667h;

carbon dioxide; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h; Further stages.;
DOI:10.1021/jo026686q

Reference yield:

: 6110-37-8
methyl 2,4-dimethoxy-6-methylbenzoate

: 656809-49-3
2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaOH / H₂O; methanol / 24 h / 60 °C

2.1: 85 percent / PPh₃; diisopropylazodicarboxylate / tetrahydrofuran / 3.67 h / 0 - 20 °C

3.1: n-BuLi; iPr₂NH / hexane; tetrahydrofuran / 0.42 h / -78 °C

3.2: 85 percent / tetrahydrofuran; hexane / 0.25 h / -78 °C

With sodium hydroxide; n-butyllithium; di-isopropyl azodicarboxylate; diisopropylamine; triphenylphosphine; In tetrahydrofuran; methanol; hexane; water;
DOI:10.1021/jo026686q

Reference yield:

: 3187-58-4
methyl orsellinate

: 656809-49-3
2-carboxymethyl-4,6-dimethoxybenzoic acid 2-trimethylsilanylethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: LiOH*H₂O / tetrahydrofuran / 0.17 h / 20 °C

1.2: 86 percent / tetrahydrofuran / 3 h / 50 °C

2.1: NaOH / H₂O; methanol / 24 h / 60 °C

3.1: 85 percent / PPh₃; diisopropylazodicarboxylate / tetrahydrofuran / 3.67 h / 0 - 20 °C

4.1: n-BuLi; iPr₂NH / hexane; tetrahydrofuran / 0.42 h / -78 °C

4.2: 85 percent / tetrahydrofuran; hexane / 0.25 h / -78 °C

With lithium hydroxide; sodium hydroxide; n-butyllithium; di-isopropyl azodicarboxylate; diisopropylamine; triphenylphosphine; In tetrahydrofuran; methanol; hexane; water;
DOI:10.1021/jo026686q