4-hydroxy-N-methyl-3-nitrobenzeneacetamide

Base Information

Chemical Name:4-hydroxy-N-methyl-3-nitrobenzeneacetamide
CAS No.:70382-04-6
Molecular Formula:C₉H₁₀N₂O₄
Molecular Weight:210.189
Hs Code.:
DSSTox Substance ID:DTXSID101267579

Synonyms:4-hydroxy-N-methyl-3-nitrobenzeneacetamide;70382-04-6;SCHEMBL8729537;MEHOGVKQEPZGGN-UHFFFAOYSA-N;DTXSID101267579;4-hydroxy-N-methyl-3 -nitrobenzeneacetamide

Suppliers and Price of 4-hydroxy-N-methyl-3-nitrobenzeneacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-hydroxy-N-methyl-3-nitrobenzeneacetamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:210.06405680
Heavy Atom Count:15
Complexity:251

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)CC1=CC(=C(C=C1)O)[N+](=O)[O-]

Technology Process of 4-hydroxy-N-methyl-3-nitrobenzeneacetamide

There total 3 articles about 4-hydroxy-N-methyl-3-nitrobenzeneacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 10463-21-5
3-nitro-4-hydroxyphenylacetyl chloride

: 74-89-5
methylamine

: 70382-04-6
4-hydroxy-N-methyl-3-nitrobenzeneacetamide

Guidance literature:: In dichloromethane; Ambient temperature;
DOI:10.1021/jm00380a017

Reference yield:

: 10463-20-4
4-hydroxy-3-nitrophenylacetic acid

: 70382-04-6
4-hydroxy-N-methyl-3-nitrobenzeneacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / SOCl₂ / 0.75 h / Heating

2: 75 percent / CH₂Cl₂ / Ambient temperature

With thionyl chloride; In dichloromethane;
DOI:10.1021/jm00380a017