C₂₅H₃₀N₂O₃

Base Information

• Chemical Name: C₂₅H₃₀N₂O₃
• CAS No.: 1373119-46-0
• Molecular Formula: C₂₅H₃₀N₂O₃
• Molecular Weight: 406.525
• Mol file: 1373119-46-0.mol

Synonyms:C₂₅H₃₀N₂O₃

Chemical Property of C₂₅H₃₀N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₀N₂O₃

There total 8 articles about C₂₅H₃₀N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H24N2O (1373119-45-9) + benzyl chloroformate (501-53-1,94274-21-2) → C25H30N2O3 (1373119-46-0)

Guidance literature:

With sodium hydroxide; In water; at 0 ℃; for 0.833333h; Inert atmosphere;

DOI:10.1021/ol300735g

Reference yield:

phenylhydrazine (100-63-0) → C25H30N2O3 (1373119-46-0)

Guidance literature:

Multi-step reaction with 5 steps

1: methanesulfonic acid / methanol / 24 h / Inert atmosphere; Reflux

2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran; water / 0.33 h / 0 °C / Inert atmosphere

3: hydroxylamine hydrochloride / pyridine / 9 h / 20 °C / Inert atmosphere

4: diisobutylaluminium hydride / hexane; dichloromethane / -78 - 20 °C / Inert atmosphere

5: sodium hydroxide / water / 0.83 h / 0 °C / Inert atmosphere

With methanesulfonic acid; hydroxylamine hydrochloride; diisobutylaluminium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium hydroxide; In tetrahydrofuran; pyridine; methanol; hexane; dichloromethane; water;

DOI:10.1021/ol300735g

Reference yield:

C16H23N → C25H30N2O3 (1373119-46-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 168 h / 20 °C / Inert atmosphere

1.2: 3 h / Inert atmosphere

2.1: methanesulfonic acid / methanol / 24 h / Inert atmosphere; Reflux

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / tetrahydrofuran; water / 0.33 h / 0 °C / Inert atmosphere

4.1: hydroxylamine hydrochloride / pyridine / 9 h / 20 °C / Inert atmosphere

5.1: diisobutylaluminium hydride / hexane; dichloromethane / -78 - 20 °C / Inert atmosphere

6.1: sodium hydroxide / water / 0.83 h / 0 °C / Inert atmosphere

With methanesulfonic acid; hydroxylamine hydrochloride; diisobutylaluminium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium hydroxide; In tetrahydrofuran; pyridine; methanol; hexane; dichloromethane; water;

DOI:10.1021/ol300735g

upstream raw materials:

(R)-(-)-1-ethyl-2-oxocyclohexane-1-propanoic acid methyl ester

(R)-(-)-methyl 1-ethyl-1,2,3,4-tetrahydrocarbazole-1-propionate

(R)-(-)-1-ethyl-1-(2'-methoxycarbonyl)ethyl-1,2,3,4-tetrahydrocarbazole-4-one

(R)-(-)-1-ethyl-1-(2'-methoxycarbonyl)ethyl-1,2,3,4-tetrahydrocarbazole-4-one oxime

Downstream raw materials:

(R)-(+)-1-benzyloxycarbonyl-4a-ethyl-2,3,4,4a,5,6-hyxahydroazepino[4,3,2-hi]benz[b]indolizin-7(1H)-one