Cbz-L-Met-L-Tyr-OH

Base Information

• Chemical Name: Cbz-L-Met-L-Tyr-OH
• CAS No.: 106861-80-7
• Molecular Formula: C₂₂H₂₆N₂O₆S
• Molecular Weight: 446.524
• Mol file: 106861-80-7.mol

Synonyms:Cbz-L-Met-L-Tyr-OH

Chemical Property of Cbz-L-Met-L-Tyr-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cbz-L-Met-L-Tyr-OH

There total 4 articles about Cbz-L-Met-L-Tyr-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H21NO6S + L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → Cbz-L-Met-L-Tyr-OH (106861-80-7)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; for 0.5h; Green chemistry;

DOI:10.1246/bcsj.20170035

Reference yield:

Cbz-Met-OH (1152-62-1) → Cbz-L-Met-L-Tyr-OH (106861-80-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 0.5 h / 0 °C

2: sodium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C / Green chemistry

With triethylamine; sodium hydroxide; In tetrahydrofuran; water;

DOI:10.1246/bcsj.20170035

Reference yield:

N-(N-benzyloxycarbonyl-L-methionyl)-L-tyrosine ethyl ester → Cbz-L-Met-L-Tyr-OH (106861-80-7)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

Cbz-Met-OH

L-tyrosine methyl ester HCl

L-tyrosine

Downstream raw materials:

Met-Tyr-OH