(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

Base Information

Chemical Name:(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane
CAS No.:1207986-37-5
Molecular Formula:C₂₃H₂₈ClNO
Molecular Weight:369.934
Hs Code.:

Synonyms:(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

Suppliers and Price of (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

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Technology Process of (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

There total 1 articles about (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1207986-35-3
(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)cyclohexyl isocyanate

: 1207986-37-5
(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

Guidance literature:: (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)cyclohexyl isocyanate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Reflux;

With sodium hydroxide; In tetrahydrofuran; at 90 ℃; for 1h; Inert atmosphere;
DOI:10.1246/bcsj.82.1528

Reference yield: 85.0%

: 1207986-37-5
(1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane

: 100477-72-3,33643-46-8,33643-49-1
(S)-ketamine

Guidance literature:: (1R,2E)-2-(3-benzyloxypropylidene)-1-(2-chlorophenyl)-1-methylaminocyclohexane; With hydrogenchloride; In water; Inert atmosphere;

With ozone; In methanol; at -78 ℃; Further stages;
DOI:10.1246/bcsj.82.1528