5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine

Base Information

• Chemical Name: 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine
• CAS No.: 86864-31-5
• Molecular Formula: C₃₀H₃₉NOSSi
• Molecular Weight: 489.797
• Mol file: 86864-31-5.mol

Synonyms:5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine

Chemical Property of 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine

There total 4 articles about 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

Triphenylmethanesulfenamide (38499-08-0) + 5-((tert-butyldimethylsilyl)oxy)pentan-2-one (86864-59-7) → 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine (86864-31-5)

Guidance literature:

With pyridinium p-toluenesulfonate; magnesium sulfate; In dichloromethane; for 7h; Ambient temperature;

DOI:10.1021/jo00168a031

Reference yield:

triphenylmethanethiol (3695-77-0) → 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine (86864-31-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / Sulfuryl chloride / toluene; diethyl ether / 2 h / 0 °C

2: 78 percent / 29 percent NH₄OH/H₂O / CH₂Cl₂ / 0 °C

3: 70 percent / Pyridinium p-toluenesulfonate, (PPTS)/anhydr. MgSO₄ / CH₂Cl₂ / 7 h / Ambient temperature

With ammonium hydroxide; sulfuryl dichloride; water; pyridinium p-toluenesulfonate; magnesium sulfate; In diethyl ether; dichloromethane; toluene;

DOI:10.1021/jo00168a031

Reference yield:

tritylsulfenyl chloride (24165-03-5) → 5-<(tert-Butyldimethylsilyl)oxy>-2-pentanone Tritylsulfenimine (86864-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / 29 percent NH₄OH/H₂O / CH₂Cl₂ / 0 °C

2: 70 percent / Pyridinium p-toluenesulfonate, (PPTS)/anhydr. MgSO₄ / CH₂Cl₂ / 7 h / Ambient temperature

With ammonium hydroxide; water; pyridinium p-toluenesulfonate; magnesium sulfate; In dichloromethane;

DOI:10.1021/jo00168a031

upstream raw materials:

Triphenylmethanesulfenamide

5-((tert-butyldimethylsilyl)oxy)pentan-2-one

2-(tert-butyldimethylsilyloxy)ethyl bromide

N-tritylsulfenyl imine of acetone

Downstream raw materials:

C₃₃H₄₃NOSSi