2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile

Base Information

• Chemical Name: 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile
• CAS No.: 147675-35-2
• Molecular Formula: C₁₄H₁₀Cl₂N₄
• Molecular Weight: 305.166
• Mol file: 147675-35-2.mol

Synonyms:2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile

Chemical Property of 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile

There total 6 articles about 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione (147675-06-7) → 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile (147675-35-2)

Guidance literature:

With chlorine; In chloroform; for 2h;

DOI:10.1246/bcsj.66.555

Reference yield:

3-(4-chlorophenylhydrazono)-2,4-pentanedione (24756-07-8) → 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile (147675-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / C₂H₅ONa / ethanol / 1 h / Heating

2: 55 percent / gaseous Cl₂ / CHCl₃ / 2 h

With sodium ethanolate; chlorine; In ethanol; chloroform;

DOI:10.1246/bcsj.66.555

Reference yield:

p-chlorobenzenediazonium chloride (2028-74-2) → 2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile (147675-35-2)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate / ethanol / 0 °C

2: 95 percent / C₂H₅ONa / ethanol / 1 h / Heating

3: 55 percent / gaseous Cl₂ / CHCl₃ / 2 h

With sodium ethanolate; sodium acetate; chlorine; In ethanol; chloroform;

DOI:10.1246/bcsj.66.555

upstream raw materials:

5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione

p-chlorobenzenediazonium chloride

3-(4-chlorophenylhydrazono)-2,4-pentanedione

acetylacetone