5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione

Base Information

• Chemical Name: 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione
• CAS No.: 147675-06-7
• Molecular Formula: C₁₄H₁₁ClN₄S
• Molecular Weight: 302.787
• Mol file: 147675-06-7.mol

Synonyms:5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione

Chemical Property of 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione

There total 5 articles about 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Cyanothioacetamide (7357-70-2) + 3-(4-chlorophenylhydrazono)-2,4-pentanedione (24756-07-8) → 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione (147675-06-7)

Guidance literature:

With sodium ethanolate; In ethanol; for 1h; Heating;

DOI:10.1246/bcsj.66.555

Reference yield:

p-chlorobenzenediazonium chloride (2028-74-2) → 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione (147675-06-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / ethanol / 0 °C

2: 95 percent / C₂H₅ONa / ethanol / 1 h / Heating

With sodium ethanolate; sodium acetate; In ethanol;

DOI:10.1246/bcsj.66.555

Reference yield:

acetylacetone (123-54-6,81235-32-7) → 5-(4-chlorophenylazo)-3-cyano-4,6-dimethyl-pyridine-2-(1H)-thione (147675-06-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / ethanol / 0 °C

2: 95 percent / C₂H₅ONa / ethanol / 1 h / Heating

With sodium ethanolate; sodium acetate; In ethanol;

DOI:10.1246/bcsj.66.555

upstream raw materials:

Cyanothioacetamide

3-(4-chlorophenylhydrazono)-2,4-pentanedione

p-chlorobenzenediazonium chloride

acetylacetone

Downstream raw materials:

Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[5-(4-chloro-phenylazo)-3-cyano-4,6-dimethyl-2-thioxo-2H-pyridin-1-yl]-tetrahydro-pyran-3-yl ester

Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[5-(4-chloro-phenylazo)-3-cyano-4,6-dimethyl-2-thioxo-2H-pyridin-1-yl]-tetrahydro-pyran-3-yl ester

2-Chloro-5-(4-chloro-phenylazo)-4,6-dimethyl-nicotinonitrile