Bis(diethylamino)(4-methoxyphenyl)phospine

Base Information

• Chemical Name: Bis(diethylamino)(4-methoxyphenyl)phospine
• CAS No.: 311820-22-1
• Molecular Formula: C₁₅H₂₇N₂OP
• Molecular Weight: 282.366
• Mol file: 311820-22-1.mol

Synonyms:Bis(diethylamino)(4-methoxyphenyl)phospine

Chemical Property of Bis(diethylamino)(4-methoxyphenyl)phospine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bis(diethylamino)(4-methoxyphenyl)phospine

There total 4 articles about Bis(diethylamino)(4-methoxyphenyl)phospine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methoxy-phenyldibromphosphan (86153-21-1) + diethylamine (109-89-7) → Bis(diethylamino)(4-methoxyphenyl)phospine (311820-22-1)

Guidance literature:

In toluene; at 0 - 20 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0033-1339548

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) → Bis(diethylamino)(4-methoxyphenyl)phospine (311820-22-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: n-butyllithium / diethyl ether; hexane / 0.17 h / -78 °C / Inert atmosphere; Schlenk technique

1.2: -78 - 20 °C / Inert atmosphere; Schlenk technique

2.1: toluene / 3 h / 100 °C / Inert atmosphere; Schlenk technique

3.1: carbon tetrabromide / toluene / 3 h / 100 °C / Inert atmosphere; Schlenk technique

4.1: toluene / 0.5 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

With n-butyllithium; carbon tetrabromide; In diethyl ether; hexane; toluene;

DOI:10.1055/s-0033-1339548

Reference yield:

C13H15OP (1480331-85-8) → Bis(diethylamino)(4-methoxyphenyl)phospine (311820-22-1)

Guidance literature:

Multi-step reaction with 3 steps

1: toluene / 3 h / 100 °C / Inert atmosphere; Schlenk technique

2: carbon tetrabromide / toluene / 3 h / 100 °C / Inert atmosphere; Schlenk technique

3: toluene / 0.5 h / 0 - 20 °C / Inert atmosphere; Schlenk technique

With carbon tetrabromide; In toluene;

DOI:10.1055/s-0033-1339548

upstream raw materials:

4-Methoxy-phenyldibromphosphan

diethylamine

1-bromo-4-methoxy-benzene

C₁₃H₁₅OP

Downstream raw materials:

C₁₅H₂₇N₂OPS