Methyl 4-(2-fluoroethoxy)benzoate

Base Information

Chemical Name:Methyl 4-(2-fluoroethoxy)benzoate
CAS No.:132838-34-7
Molecular Formula:C₁₀H₁₁FO₃
Molecular Weight:198.194
Hs Code.:
European Community (EC) Number:848-722-2

Synonyms:Methyl 4-(2-fluoroethoxy)benzoate;132838-34-7;SCHEMBL1881566;KODIHNQWZAHXMW-UHFFFAOYSA-N;methyl-4-(2-fluoroethoxyl)benzoate;methyl 4-(2-fluoroethyloxy)benzoate;AKOS017569639;EN300-7541193;Z1269321292

Suppliers and Price of Methyl 4-(2-fluoroethoxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 4-(2-fluoroethoxy)benzoate

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:198.06922237
Heavy Atom Count:14
Complexity:176

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC=C(C=C1)OCCF

Technology Process of Methyl 4-(2-fluoroethoxy)benzoate

There total 4 articles about Methyl 4-(2-fluoroethoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 762-49-2
2-fluoroethyl bromide

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 132838-34-7
methyl-4-(2-fluoroethoxyl)benzoate

Guidance literature:: methyl 4-hydroxylbenzoate; With potassium carbonate; In acetone; for 0.5h; Reflux;

2-fluoroethyl bromide; In acetone; for 20h; Reflux;
DOI:10.1021/acs.jmedchem.6b00390

Reference yield: 85.0%

: 762-49-2
2-fluoroethyl bromide

: 132838-34-7
methyl-4-(2-fluoroethoxyl)benzoate

Guidance literature:: methyl 4-hydroxylbenzoate; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 5 - 20 ℃; for 3.33333h;

2-fluoroethyl bromide; In DMF (N,N-dimethyl-formamide); at 50 ℃; for 18h;

Reference yield: 71.0%

: 67-56-1
methanol

: 702-18-1
1-Fluor-2-(p-methyl)phenoxyethan

: 132838-34-7
methyl-4-(2-fluoroethoxyl)benzoate

Guidance literature:: With tetradecyl(tributyl)phosphonium methanesulfonate; at 20 ℃; for 18h; Inert atmosphere; Electrolysis; Sealed tube; Green chemistry;
DOI:10.1002/chem.202005158