N-(4-bromophenyl)-2-iodobenzamide

Base Information

• Chemical Name: N-(4-bromophenyl)-2-iodobenzamide
• CAS No.: 313268-47-2
• Molecular Formula: C₁₃H₉BrINO
• Molecular Weight: 402.029
• European Community (EC) Number: 644-922-7
• Mol file: 313268-47-2.mol

Synonyms:N-(4-bromophenyl)-2-iodobenzamide;2-iodo-N-(4-bromophenyl)benzamide;AKOS001604773;EU-0003101;SR-01000414645;SR-01000414645-1

Chemical Property of N-(4-bromophenyl)-2-iodobenzamide

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 400.89122
• Heavy Atom Count: 17
• Complexity: 266

Purity/Quality:

N-(4-BROMOPHENYL)-2-IODOBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)Br)I

Technology Process of N-(4-bromophenyl)-2-iodobenzamide

There total 2 articles about N-(4-bromophenyl)-2-iodobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-Iodobenzoyl chloride (609-67-6) + 4-bromo-aniline (106-40-1) → 2-iodo N-(4-bromophenyl)benzamide (313268-47-2)

Guidance literature:

With sodium hydroxide; In dichloromethane; at 0 - 20 ℃; for 20h;

DOI:10.3390/molecules25153354

Reference yield: 80.0%

2-Iodobenzoic acid (88-67-5) + 4-bromo-aniline (106-40-1) → 2-iodo N-(4-bromophenyl)benzamide (313268-47-2)

Guidance literature:

2-Iodobenzoic acid; With thionyl chloride; triethylamine; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

4-bromo-aniline; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1002/adsc.201500642

Reference yield: 90.0%

carbon monoxide (201230-82-2) + 2-iodo N-(4-bromophenyl)benzamide (313268-47-2) → 2-(4-bromophenyl)isoindoline-1,3-dione (40101-31-3)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In toluene; at 110 ℃; for 26h;

DOI:10.1002/adsc.201500642

upstream raw materials:

2-Iodobenzoyl chloride

4-bromo-aniline

2-Iodobenzoic acid

Downstream raw materials:

2-(4-bromophenyl)-1,2-benzisothiazol-3(2H)-one

2-bromo-6-(5H)-phenanthridinone

2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one

2-(4-bromophenyl)isoindoline-1,3-dione