anti-2-phenyl-5-hexen-3-ol

Base Information

• Chemical Name: anti-2-phenyl-5-hexen-3-ol
• CAS No.: 74333-46-3
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.258
• Mol file: 74333-46-3.mol

Synonyms:anti-2-phenyl-5-hexen-3-ol

Chemical Property of anti-2-phenyl-5-hexen-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of anti-2-phenyl-5-hexen-3-ol

There total 27 articles about anti-2-phenyl-5-hexen-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

Allyl acetate (591-87-7) + 2-Phenylpropanal (34713-70-7) → anti-2-phenyl-5-hexen-3-ol (74333-46-3)

Guidance literature:

With nickel(II) bromide dimethoxyethane; 1,10-Phenanthroline; tris(2,2'-bipyridyl)ruthenium dichloride; N-ethyl-N,N-diisopropylamine; In water; acetonitrile; at 20 ℃; for 48h; Schlenk technique; Inert atmosphere; Irradiation;

DOI:10.1039/c9cc03344k

Reference yield:

4,4,5,5-tetramethyl-2-(2-phenylhex-5-en-3-yl)-1,3,2-dioxaborolane → anti-2-phenyl-5-hexen-3-ol (74333-46-3) + phenyl-2 hexene-5 ol-3 (74333-47-4)

Guidance literature:

With sodium perborate; In tetrahydrofuran; water; at 20 ℃; for 2h; Overall yield = 85 %; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0036-1588811

Reference yield:

2-Phenylpropanal (34713-70-7) + allyl-trimethyl-silane (762-72-1) → anti-2-phenyl-5-hexen-3-ol (74333-46-3) + phenyl-2 hexene-5 ol-3 (74333-47-4)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at -78 ℃; for 0.0833333h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/ja00222a050

upstream raw materials:

9-allyl-9-bora-bicyclo[3.3.1]nonane

2-Phenylpropanal

allylmagnesium bromide

allyltributylstanane