Technology Process of 5-chloro-2,3-dihydroxyphenylacetic acid
There total 14 articles about 5-chloro-2,3-dihydroxyphenylacetic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
aluminum tri-bromide;
In
benzene;
for 3h;
Heating;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 45 percent / chlorine / acetic acid / 5 h / 20 °C
2: 1) 99percent hydrazine hydrate, 2) KOH / 1) reflux, 5 h, 2) reflux, 5 h
3: 75 percent / K2CO3 / acetone / 5 h / Heating
4: 77 percent / KMnO4 / H2O / 5 h / Heating
5: SOCl2 / 2 h / Heating
6: diethyl ether / 10 h / 20 °C
7: 45 percent / silver oxide / dioxane; H2O / 1 h / 95 °C
8: 88 percent / AlBr3 / benzene / 3 h / Heating
With
potassium hydroxide; potassium permanganate; thionyl chloride; aluminum tri-bromide; chlorine; potassium carbonate; hydrazine hydrate; silver(l) oxide;
In
1,4-dioxane; diethyl ether; water; acetic acid; acetone; benzene;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1) 99percent hydrazine hydrate, 2) KOH / 1) reflux, 5 h, 2) reflux, 5 h
2: 75 percent / K2CO3 / acetone / 5 h / Heating
3: 77 percent / KMnO4 / H2O / 5 h / Heating
4: SOCl2 / 2 h / Heating
5: diethyl ether / 10 h / 20 °C
6: 45 percent / silver oxide / dioxane; H2O / 1 h / 95 °C
7: 88 percent / AlBr3 / benzene / 3 h / Heating
With
potassium hydroxide; potassium permanganate; thionyl chloride; aluminum tri-bromide; potassium carbonate; hydrazine hydrate; silver(l) oxide;
In
1,4-dioxane; diethyl ether; water; acetone; benzene;
