7-CHLORO-2,4-DIMETHYLQUINOLINE

Base Information

• Chemical Name: 7-CHLORO-2,4-DIMETHYLQUINOLINE
• CAS No.: 88499-96-1
• Molecular Formula: C₁₁H₁₀ClN
• Molecular Weight: 191.66
• Hs Code.: 2933499090
• Mol file: 88499-96-1.mol

Synonyms:7-Chloro-2,4-dimethylquinoline

Chemical Property of 7-CHLORO-2,4-DIMETHYLQUINOLINE

Chemical Property:

• Vapor Pressure: 0.00216mmHg at 25°C
• Refractive Index: 1.621
• Boiling Point: 299.2°C at 760 mmHg
• Flash Point: 163°C
• PSA: 12.89000
• Density: 1.188g/cm³
• LogP: 3.50500

Purity/Quality:

98%min ^*data from raw suppliers

7-Chloro-2,4-dimethylquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-CHLORO-2,4-DIMETHYLQUINOLINE

There total 6 articles about 7-CHLORO-2,4-DIMETHYLQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

methanol (67-56-1) + 2-methyl-7-chloroquinoline (4965-33-7) → 7-chloro-2,4-dimethyl-quinoline (88499-96-1)

Guidance literature:

With hydrogenchloride; In water; for 8h; Inert atmosphere; UV-irradiation;

DOI:10.1039/c7sc03768f

Reference yield:

4-(3-chlorophenylamino)-3-penten-2-one (94418-01-6) → 7-chloro-2,4-dimethyl-quinoline (88499-96-1)

Guidance literature:

With sulfuric acid; at 130 - 140 ℃;

Reference yield:

3-chloro-aniline (108-42-9) → 7-chloro-2,4-dimethyl-quinoline (88499-96-1)

Guidance literature:

Multi-step reaction with 2 steps

2: concentrated sulfuric acid / 130 - 140 °C

With sulfuric acid;

upstream raw materials:

4-(3-chlorophenylamino)-3-penten-2-one

3-chloro-aniline

acetone

paracetaldehyde

Refernces