Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)

Base Information

Chemical Name:Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)
CAS No.:88326-59-4
Molecular Formula:C8H9 N O2
Molecular Weight:151.165
Hs Code.:
Mol file:88326-59-4.mol

Synonyms:Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)

Suppliers and Price of Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)

Chemical Property:

PSA：50.09000
LogP:0.87528

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI)

There total 3 articles about Cyclopropanecarboxylic acid, 1-cyano-2-ethenyl-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 6974-12-5
1,4-dibromo-2-butene

: 105-34-0
methyl 2-cyanoacetate

: 88326-59-4
methyl 1-cyano-2-vinylcyclopropanecarboxylate

Guidance literature:: With caesium carbonate; In tetrahydrofuran; at 60 ℃; Inert atmosphere;
DOI:10.1021/ja300294a

Reference yield:

: 1476-11-5
Z-1,4-dichlorobutene

: 105-34-0
methyl 2-cyanoacetate

: 88326-52-7
Methyl 1-cyano-3-cyclopentenecarboxylate

: 88326-59-4
methyl 1-cyano-2-vinylcyclopropanecarboxylate

Guidance literature:: With lithium hydride; Yield given. Multistep reaction. Yields of byproduct given; 1) 1,2-dimethoxyethane, 5 h, 2) r.t., 72 h;
DOI:10.1021/jo00179a035

Reference yield:

: 821-06-7
(E)-1,4-dibromobutene

: 105-34-0
methyl 2-cyanoacetate

: 88326-59-4
methyl 1-cyano-2-vinylcyclopropanecarboxylate

Guidance literature:: methyl 2-cyanoacetate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h; Inert atmosphere;

(E)-1,4-dibromobutene; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/c4cc07839j