ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

Base Information

Chemical Name:ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate
CAS No.:337519-72-9
Molecular Formula:C₃₀H₃₇N₃O₇S
Molecular Weight:583.706
Hs Code.:

Synonyms:ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

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Chemical Property of ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

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Technology Process of ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

There total 1 articles about ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 290332-75-1
ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}sulfamoyl)acetate

: 141-78-6
ethyl acetate

: 1972-28-7,218603-74-8
diethylazodicarboxylate

: 98116-50-8
3-(3-cyanophenyl)-2-(E)-propen-1-ol

: 337519-72-9
ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

Guidance literature:: With triphenylphosphine; In dichloromethane;

Reference yield: 68.0%

: 337519-72-9
ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate

: ethyl {N-[(E)-3-(3-amidinophenyl)-2-propenyl]-N-[4-(piperidin-4-yloxy)phenyl]sulfamoyl}acetate dihydrochloride

Guidance literature:: ethyl (N-{4-[1-(t-butoxycarbonyl)piperidin-4-yloxy]phenyl}-N-[(E)-3-(3-cyanophenyl)-2-propenyl]sulfamoyl)acetate; With hydrogenchloride; ethanol; In dichloromethane; at 0 - 20 ℃; for 9h;

With ammonia; ammonium chloride; In ethanol; water; at 20 ℃; for 12h;

With hydrogenchloride; In 1,4-dioxane; ethanol; water;