potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Base Information

Chemical Name:potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate
CAS No.:872221-56-2
Molecular Formula:C₂₈H₃₇N₂O₇*K
Molecular Weight:552.709
Hs Code.:

Synonyms:potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Suppliers and Price of potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

There total 10 articles about potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 719307-48-9
(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyric acid

: 872221-56-2
potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Guidance literature:: With potassium tert-butylate; In 2-methyl-propan-1-ol; ethyl acetate; at 20 ℃;

Reference yield:

: (S)-2-Benzyloxycarbonylamino-succinic acid 1-ethyl ester; compound with dicyclohexyl-amine

: 872221-56-2
potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Guidance literature:: Multi-step reaction with 10 steps

1: sulfuric acid; water / diethyl ether / 18 h / Heating / reflux

2: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 18 h / 20 °C

3: triethylamine / dichloromethane / 4 h / 0 - 20 °C

4: trichlorophosphate / toluene / 1.5 h / 100 °C

5: hydrogen bromide; acetic acid / 1 h / 20 °C

6: hydrogenchloride / diethyl ether

7: toluene / 18 h / 70 °C / Azeotropic distillation

8: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C

9: trifluoroacetic acid / toluene / 18 h / 20 °C / Azeotropic distillation

10: potassium tert-butylate / 2-methyl-propan-1-ol; ethyl acetate / 20 °C

With 4-methyl-morpholine; hydrogenchloride; thionyl chloride; sulfuric acid; potassium tert-butylate; water; hydrogen bromide; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; trichlorophosphate; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; 2-methyl-propan-1-ol; ethyl acetate; toluene;

Reference yield:

: 4668-43-3
(S)-3-(benzyloxycarbonylamino)-4-ethoxy-4-oxobutanoic acid

: 872221-56-2
potassium-(2S)-2-{1-[(1S)-1-isobutoxycarbonyl-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}4-methoxy-butyrate

Guidance literature:: Multi-step reaction with 9 steps

1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 18 h / 20 °C

2: triethylamine / dichloromethane / 4 h / 0 - 20 °C

3: trichlorophosphate / toluene / 1.5 h / 100 °C

4: hydrogen bromide; acetic acid / 1 h / 20 °C

5: hydrogenchloride / diethyl ether

6: toluene / 18 h / 70 °C / Azeotropic distillation

7: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 18 h / 20 °C

8: trifluoroacetic acid / toluene / 18 h / 20 °C / Azeotropic distillation

9: potassium tert-butylate / 2-methyl-propan-1-ol; ethyl acetate / 20 °C

With 4-methyl-morpholine; hydrogenchloride; thionyl chloride; potassium tert-butylate; hydrogen bromide; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid; trichlorophosphate; N,N-dimethyl-formamide; In diethyl ether; dichloromethane; 2-methyl-propan-1-ol; ethyl acetate; toluene;