(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Base Information

Chemical Name:(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide
CAS No.:865872-73-7
Molecular Formula:C₂₄H₂₈O₆
Molecular Weight:412.483
Hs Code.:

Synonyms:(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Suppliers and Price of (3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

There total 8 articles about (3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 868128-07-8
2,2-dimethyl-propionic acid 2-(4-benzyloxy-3-methoxy-phenyl)-5-hydroxy-tetrahydro-furan-3-ylmethyl ester

: 865872-73-7
(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Guidance literature:: With 4 A molecular sieve; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 16h;
DOI:10.1271/bbb.69.113

Reference yield:

: 865872-70-4
(2S)-2-[(S)-(4-benzyloxy-3-methoxyphenyl)(triisopropylsilyloxy)methyl]-4-penten-1-ol

: 865872-73-7
(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

2: OsO₄; 4-methylmorpholine N-oxide / H₂O; 2-methyl-propan-2-ol; acetone / 16 h / 20 °C

3: 13.6 g / NaIO₄ / methanol / 1 h / 20 °C

4: 94 percent / (n-Bu)4NF / tetrahydrofuran / 1 h / 0 °C

5: 82 percent / pyridinium chlorochrmoate; molecular sieves 4 Angstroem / CH₂Cl₂ / 16 h / 20 °C

With pyridine; sodium periodate; osmium(VIII) oxide; 4 A molecular sieve; tetrabutyl ammonium fluoride; 4-methylmorpholine N-oxide; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane; water; acetone; tert-butyl alcohol;
DOI:10.1271/bbb.69.113

Reference yield:

: 865872-72-6
(2S)-2-[(S)-(4-benzyloxy-3-methoxyphenyl)(triisopropylsilyloxy)methyl]-3-formylpropyl pivaloate

: 865872-73-7
(3S,4S)-4-(4-benzyloxy-3-methoxyphenyl)-3-pivaloyloxymethyl-4-butanolide

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / (n-Bu)4NF / tetrahydrofuran / 1 h / 0 °C

2: 82 percent / pyridinium chlorochrmoate; molecular sieves 4 Angstroem / CH₂Cl₂ / 16 h / 20 °C

With 4 A molecular sieve; tetrabutyl ammonium fluoride; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;
DOI:10.1271/bbb.69.113