(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Base Information

Chemical Name:(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene
CAS No.:865872-71-5
Molecular Formula:C₃₄H₅₂O₅Si
Molecular Weight:568.869
Hs Code.:

Synonyms:(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Suppliers and Price of (4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

There total 5 articles about (4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 865872-70-4
(2S)-2-[(S)-(4-benzyloxy-3-methoxyphenyl)(triisopropylsilyloxy)methyl]-4-penten-1-ol

: 3282-30-2
pivaloyl chloride

: 865872-71-5
(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1271/bbb.69.113 DOI:10.1021/np050089s

Reference yield:

: 865872-68-0
(4S)-4-benzyl-3-{(R)-2-[(S)-(4-benzyloxy-3-methoxyphenyl)(hydroxy)methyl]-4-pentenoyl}-2-oxazolidinone

: 865872-71-5
(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / 2,6-lutidine / CH₂Cl₂ / 1.5 h / 0 °C

2: 61 percent / LiBH₄; methanol / tetrahydrofuran / 16 h / 20 °C

3: 100 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

With pyridine; 2,6-dimethylpyridine; methanol; lithium borohydride; In tetrahydrofuran; dichloromethane;
DOI:10.1271/bbb.69.113

Reference yield:

: 865872-69-1
(4S)-4-benzyl-3-{(R)-2-[(S)-(4-benzyloxy-3-methoxyphenyl)(triisopropylsilyloxy)methyl]-4-pentenoyl}-2-oxazolidinone

: 865872-71-5
(4S,5S)-5-(4-benzyloxy-3-methoxyphenyl)-4-pivaloyloxymethyl-5-(triisopropylsilyloxy)-1-pentene

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / LiBH₄; methanol / tetrahydrofuran / 16 h / 20 °C

2: 100 percent / pyridine / CH₂Cl₂ / 2 h / 20 °C

With pyridine; methanol; lithium borohydride; In tetrahydrofuran; dichloromethane;
DOI:10.1271/bbb.69.113