(S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid

Base Information

Chemical Name:(S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid
CAS No.:83345-44-2
Molecular Formula:C9H17 N O5
Molecular Weight:219.238
Hs Code.:2924199090
DSSTox Substance ID:DTXSID10478392
Mol file:83345-44-2.mol

Synonyms:83345-44-2;(S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid;Boc-HoSer-OH;(S)-N-Boc-3-amino-4-hydroxybutyric acid;(3S)-4-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid;MFCD00270243;SCHEMBL3682058;DTXSID10478392;AKOS016003740;CS-W006934;DS-17525;(S)-3-((Boc)amino)-4-hydroxybutanoic acid;C76663;A864273;(3S)-3-[(tert-Butoxycarbonyl)amino]-4-hydroxybutanoic acid;(3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-butanoic acid

Suppliers and Price of (S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Boc-HoSer-OH 95+%
1g
$ 293.00

Crysdot
Boc-HoSer-OH 95+%
5g
$ 880.00

Chemenu
(S)-3-((tert-butoxycarbonyl)amino)-4-hydroxybutanoicacid 95%
1g
$ 296.00

American Custom Chemicals Corporation
(S)-N-BOC-3-AMINO-4-HYDROXYBUTYRIC ACID 95.00%
5G
$ 1576.58

Ambeed
Boc-HoSer-OH 95%
5g
$ 542.00

Ambeed
Boc-HoSer-OH 95%
1g
$ 193.00

Ambeed
Boc-HoSer-OH 95%
250mg
$ 73.00

Ambeed
Boc-HoSer-OH 95%
100mg
$ 47.00

Total 20 raw suppliers

Chemical Property of (S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid

Chemical Property:

Vapor Pressure:1.08E-08mmHg at 25°C
Refractive Index:1.484
Boiling Point:416.9°C at 760 mmHg
Flash Point:205.9°C
PSA：95.86000
Density:1.204g/cm³
LogP:0.73760
Storage Temp.:2-8°C
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:219.11067264
Heavy Atom Count:15
Complexity:233

Purity/Quality:

97% ^*data from raw suppliers

Boc-HoSer-OH 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC(=O)O)CO
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC(=O)O)CO

Technology Process of (S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid

There total 11 articles about (S)-3-((tert-Butoxycarbonyl)amino)-4-hydroxybutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120409-48-5
N-t-butyloxycarbonyl-DL-aspartic acid anhydride

: 83345-44-2
3-<(tert-Butoxycarbonyl)amino>-4-hydroxy-L-butyric acid

Guidance literature:: N-t-butyloxycarbonyl-DL-aspartic acid anhydride; With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 4h;

With sodium hydrogen sulfate; water; In tetrahydrofuran;

Reference yield:

: 104227-71-6
N-[(3S)-tetrahydro-5-oxo-3-furanyl]carbamic acid-1,1-dimethylethyl ester

: 83345-44-2
3-tert-butoxycarbonylamino-4-hydroxy-butyric acid

Guidance literature:: With aq. CsCO₃; In acetone; at 20 ℃; for 3h;
DOI:10.1055/s-2003-38733

Reference yield:

: 13726-67-5
Boc-Asp-OH

: 83345-44-2
3-tert-butoxycarbonylamino-4-hydroxy-butyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / diisopropyl carbodiimide / ethyl acetate / 2 h

2: NaBH₄ / tetrahydrofuran / 16 h / 20 °C

3: aq. CsCO₃ / acetone / 3 h / 20 °C

With sodium tetrahydroborate; diisopropyl-carbodiimide; In tetrahydrofuran; ethyl acetate; acetone;
DOI:10.1055/s-2003-38733