DIETHYL ISOBUTYLIDENEMALONATE

Base Information

• Chemical Name: DIETHYL ISOBUTYLIDENEMALONATE
• CAS No.: 5652-68-6
• Molecular Formula: C11H18 O4
• Molecular Weight: 214.262
• Mol file: 5652-68-6.mol

Synonyms:Malonicacid, isobutylidene-, diethyl ester (6CI,7CI,8CI); Propanedioic acid,(2-methylpropylidene)-, diethyl ester (9CI); (2-Methylpropylidene)malonic aciddiethyl ester; Diethyl 2-(2-Methylpropylidene)malonate; Diethyl2-methylpropylidenemalonate; Diethyl isobutylidenemalonate; NSC 408239

Chemical Property of DIETHYL ISOBUTYLIDENEMALONATE

Chemical Property:

• Vapor Pressure: 0.0534mmHg at 25°C
• Boiling Point: 234.2°C at 760 mmHg
• Flash Point: 101.7°C
• PSA: 52.60000
• Density: 1.016g/cm³
• LogP: 1.69500
• Storage Temp.: Store below +30°C.

Purity/Quality:

Diethyl2-(2-Methylpropylidene)malonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL ISOBUTYLIDENEMALONATE

There total 6 articles about DIETHYL ISOBUTYLIDENEMALONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

isobutyraldehyde (78-84-2) + diethyl malonate (105-53-3) → diethyl 2-(2-methylpropylidene)malonate (5652-68-6)

Guidance literature:

With piperidine; acetic acid; In benzene; for 3h; Dean-Stark; Reflux;

DOI:10.1134/S0012500817090014

Reference yield: 82.0%

diethyl 1-isopropylideneamino-Δ2-1,2,3-triazoline-5,5-dicarboxylate → diethyl 2-(2-methylpropylidene)malonate (5652-68-6)

Guidance literature:

With boron trifluoride diethyl etherate; trifluoroacetic acid; In tetrachloromethane; for 0.5h; Heating;

Reference yield:

N,N,2-Trimethyl-1-propen-1-amin (6906-32-7) + diethyl malonate (105-53-3) → diethyl 2-(2-methylpropylidene)malonate (5652-68-6)

Guidance literature:

DOI:10.1021/jo01032a021

upstream raw materials:

isobutyraldehyde

diethyl malonate

N,N,2-Trimethyl-1-propen-1-amin

diethylmesoxalate hydrazone

Downstream raw materials:

(2-methyl-1-o-tolyl-propyl)-malonic acid diethyl ester

dihydro-5,5-dimethyl-2(3H)-furanone

4-methyl-pent-2-enoic acid

(2-methylpropyl)-propanedioic acid, diethyl ester