1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose

Base Information

• Chemical Name: 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose
• CAS No.: 877034-79-2
• Molecular Formula: C₁₉H₂₂O₅
• Molecular Weight: 330.381
• Mol file: 877034-79-2.mol

Synonyms:1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose

Chemical Property of 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose

There total 2 articles about 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-hept-1-ynitol (877034-78-1) → 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose (877034-79-2)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; for 12h;

DOI:10.1080/07328300500388693

Reference yield:

2,3,4,5-di-O-isopropylidene-D-xylose aldehyde (13039-94-6) → 1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose (877034-79-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 62 percent / tetrahydrofuran / 4 h / 20 °C

2: 52 percent / PCC / CH₂Cl₂ / 12 h

With pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;

DOI:10.1080/07328300500388693

Reference yield: 90.0%

1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-D-xylo-hept-1-yn-3-ulose (877034-79-2) + acetamidine hydrochloride (124-42-5) → 4-(1,2:3,4-di-O-isopropylidene-D-xylo-1,2,3,4-tetrahydroxybutyl)-2-methyl-6-phenylpyrimidine

Guidance literature:

With sodium carbonate; In water; ethyl acetate; for 1h; Heating;

DOI:10.1080/07328300500388693

upstream raw materials:

1,2-dideoxy-4,5:6,7-di-O-isopropylidene-1-phenyl-hept-1-ynitol

2,3,4,5-di-O-isopropylidene-D-xylose aldehyde

Downstream raw materials:

3-(1,2:3,4-di-O-isopropylidene-D-xylo-1,2,3,4-tetrahydroxybutyl)-5-phenyl-1H-pyrazole