2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose

Base Information

• Chemical Name: 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose
• CAS No.: 944471-84-5
• Molecular Formula: C₄₅H₅₂O₅S₂
• Molecular Weight: 737.037
• Mol file: 944471-84-5.mol

Synonyms:2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose

Chemical Property of 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose

There total 3 articles about 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

D-galactose-diethyl-dithioacetal (5463-33-2) + benzyl bromide (100-39-0) → 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose (944471-84-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c8cc05523h

Reference yield:

D-Galactose (59-23-4) → 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose (944471-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride

2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

2.2: 22 h / 20 °C / Inert atmosphere

With hydrogenchloride; sodium hydride; In N,N-dimethyl-formamide; mineral oil;

DOI:10.1002/chem.201202302

Reference yield:

D-Galactose (10257-28-0) → 2,3,4,5,6-penta-O-benzyl diethyl dithioacetal D-galactose (944471-84-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water / 20 °C / Inert atmosphere

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 24 h / 0 °C / Inert atmosphere

With hydrogenchloride; sodium hydride; In water; N,N-dimethyl-formamide; mineral oil;

DOI:10.1039/c8cc05523h

upstream raw materials:

D-galactose-diethyl-dithioacetal

benzyl bromide

D-Galactose

D-Galactose

Downstream raw materials:

2,3,4,5,6-penta-O-benzyl-aldehydo-D-galactose

1,1'-dideoxy-2,3,4,5,6-penta-O-benzyl-D-galacto-hept-1'-ynitol

1,1'-dideoxy-1'-(dibenzylphosphinyl)-2,3,4,5,6-penta-O-benzyl-D-galacto-hept-1'-ynitol

(E)-1,1'-dideoxy-1'-(dibenzylphosphinyl)-2,3,4,5,6-penta-O-benzyl-D-galacto-hept-1'-enitol