tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate

Base Information

• Chemical Name: tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate
• CAS No.: 82112-30-9
• Molecular Formula: C15H34 O3 Si2
• Molecular Weight: 0
• Mol file: 82112-30-9.mol

Synonyms:tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate

Chemical Property of tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate

Chemical Property:

• Melting Point: 159 - 162 °C
• PSA: 35.53000
• LogP: 4.94670

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate

There total 2 articles about tert-Butyl(dimethyl)silyl 3-([tert-butyl(dimethyl)silyl]oxy)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide (77377-52-7) + 3-hydroxypropionic acid (503-66-2) → C15H34O3Si2 (82112-30-9)

Guidance literature:

With tert-butyldimethylsilyl chloride; In acetonitrile; for 0.0833333h; Ambient temperature; other silylating agent;

DOI:10.1021/jo00138a032

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → C15H34O3Si2 (82112-30-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) sodium hydride / 1.) benzene, acetonitrile, 4 deg C, 4 h, 2.) 2 h

2: 100 percent / 1percent tert-butyldimethylsilyl chloride (TBDMSCl) / acetonitrile / 0.08 h / Ambient temperature; other silylating agent

With sodium hydride; tert-butyldimethylsilyl chloride; In acetonitrile;

DOI:10.1021/jo00138a032

upstream raw materials:

N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide

3-hydroxypropionic acid

tert-butyldimethylsilyl chloride