5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)

Base Information

Chemical Name:5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)
CAS No.:81569-41-7
Molecular Formula:C₉H₁₂BrNO₂S
Molecular Weight:278.17
Hs Code.:
Mol file:81569-41-7.mol

Synonyms:5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)

Suppliers and Price of 5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl2-bromo-4-methylthiazole-5-carboxylate 97%
5g
$ 559.00

Chemcia Scientific
2-Bromo-4-methyl-thiazole-5-carboxylicacidtert-butylester ＞97%
2.5 G
$ 500.00

Alichem
tert-Butyl2-bromo-4-methylthiazole-5-carboxylate
25g
$ 1143.45

Alichem
tert-Butyl2-bromo-4-methylthiazole-5-carboxylate
10g
$ 700.35

Alichem
tert-Butyl2-bromo-4-methylthiazole-5-carboxylate
5g
$ 448.44

Total 6 raw suppliers

Chemical Property of 5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)

Chemical Property:

Boiling Point:94-96 °C(Press: 0.1 Torr)
PKA:-0.20±0.10(Predicted)
PSA：67.43000
Density:1.448±0.06 g/cm3(Predicted)
LogP:3.16930

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl2-bromo-4-methylthiazole-5-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI)

There total 4 articles about 5-Thiazolecarboxylicacid,2-bromo-4-methyl-,1,1-dimethylethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 40003-41-6
2-bromo-4-methyl-thiazole-5-carboxylic acid

: 75-65-0
tert-butyl alcohol

: 81569-41-7
tert-butyl 2-bromo-4-methylthiazole-5-carboxylate

Guidance literature:: With sulfuric acid; magnesium sulfate; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.organomet.5b00631

Reference yield: 39.7%

: 40003-41-6
2-bromo-4-methyl-thiazole-5-carboxylic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 81569-41-7
tert-butyl 2-bromo-4-methylthiazole-5-carboxylate

Guidance literature:: With dmap; In tert-butyl alcohol; at 30 ℃; for 3h;

Reference yield:

: 22900-83-0
ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate

: 81569-41-7
tert-butyl 2-bromo-4-methylthiazole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / H₂O / Heating

2: 0.47 g / H₂SO₄

With potassium hydroxide; sulfuric acid; In water;