5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone

Base Information

• Chemical Name: 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone
• CAS No.: 76979-43-6
• Molecular Formula: C₁₈H₁₆N₂O₂S
• Molecular Weight: 324.403
• Mol file: 76979-43-6.mol

Synonyms:5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone

Chemical Property of 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone

There total 4 articles about 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-(4-methoxy-benzylidene)-2-methylsulfanyl-thiazol-4-one (28996-11-4) + benzylamine (100-46-9) → 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone (76979-43-6)

Guidance literature:

In ethanol; Heating;

Reference yield: 27.0%

4-methoxy-benzaldehyde (123-11-5) + 2-(benzylimino)thiazolidin-4-one (17385-69-2) → 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone (76979-43-6)

Guidance literature:

With sodium acetate; acetic acid; for 72h; Reflux; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.04.075

Reference yield:

5-(4-methoxybenzylidene)-2-thioxo-4-thiazolidinone (5462-97-5,81154-16-7) → 5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-4-thiazolidinone (76979-43-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / NaOH / acetone; H₂O / 3 h / Ambient temperature

2: 80 percent / ethanol / Heating

With sodium hydroxide; In ethanol; water; acetone;

upstream raw materials:

5-(4-methoxy-benzylidene)-2-methylsulfanyl-thiazol-4-one

benzylamine

5-(4-methoxybenzylidene)-2-thioxo-4-thiazolidinone

4-methoxy-benzaldehyde

Downstream raw materials:

5-(4-Methoxyphenylmethylene)-2-(phenylmethylimino)-3-methyl-4-thiazolidinone