Technology Process of N-(4-(3,4-dichlorophenyl)butan-2-yl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide
There total 4 articles about N-(4-(3,4-dichlorophenyl)butan-2-yl)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-ylidene)acetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diethyl ether / 19 h / 0 - 20 °C
2.1: ammonium acetate / methanol / 0.17 h / 20 °C
2.2: 18 h / 20 °C
3.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C
With
ammonium acetate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 18 h / 20 °C
2.1: diethyl ether / 19 h / 0 - 20 °C
3.1: ammonium acetate / methanol / 0.17 h / 20 °C
3.2: 18 h / 20 °C
4.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C
With
ammonium acetate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine;
In
methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
