(S)-Phenyl-phosphonic acid methyl ester phenyl ester

Base Information

• Chemical Name: (S)-Phenyl-phosphonic acid methyl ester phenyl ester
• CAS No.: 70741-71-8
• Molecular Formula: C₁₃H₁₃O₃P
• Molecular Weight: 248.218
• Mol file: 70741-71-8.mol

Synonyms:(S)-Phenyl-phosphonic acid methyl ester phenyl ester

Chemical Property of (S)-Phenyl-phosphonic acid methyl ester phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-Phenyl-phosphonic acid methyl ester phenyl ester

There total 2 articles about (S)-Phenyl-phosphonic acid methyl ester phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

methanol (67-56-1) → (S)-Phenyl-phosphonic acid methyl ester phenyl ester (70741-71-8)

Guidance literature:

With sulfuric acid; for 24h; Ambient temperature;

DOI:10.1055/s-1981-29607

Reference yield:

methyl phenylphosphinate (7162-15-4,111469-75-1,121467-78-5) + phenol (108-95-2,27073-41-2) → (S)-Phenyl-phosphonic acid methyl ester phenyl ester (70741-71-8) + (R)‐methyl (phenyl)‐phenyl‐phosphonate (70741-70-7)

Guidance literature:

With tetrachloromethane; (S)-(-)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 9h; Overall yield = 33 percent; Overall yield = 24.6 mg; enantioselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.3390/molecules26123661

upstream raw materials:

methanol

methyl phenylphosphinate

phenol