tert-butyl 3-fluorophenyl ether

Base Information

• Chemical Name: tert-butyl 3-fluorophenyl ether
• CAS No.: 16222-40-5
• Molecular Formula: C₁₀H₁₃FO
• Molecular Weight: 168.211
• Mol file: 16222-40-5.mol

Synonyms:tert-butyl 3-fluorophenyl ether

Chemical Property of tert-butyl 3-fluorophenyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of tert-butyl 3-fluorophenyl ether

There total 1 articles about tert-butyl 3-fluorophenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

1,3-Difluorobenzene (372-18-9) + tert-butyl alcohol (75-65-0) → tert-butyl 3-fluorophenyl ether (16222-40-5)

Guidance literature:

With 1-methyl-pyrrolidin-2-one; sodium hydride; at 100 ℃; for 2h;

DOI:10.1016/j.tetlet.2006.06.029

Reference yield:

tert-butyl 3-fluorophenyl ether (16222-40-5) → 3-fluorophenol (372-20-3)

Guidance literature:

In methanol; at 25 ℃; Kinetics; Quantum yield; Irradiation;

DOI:10.1021/jo0002893

upstream raw materials:

1,3-Difluorobenzene

tert-butyl alcohol

Downstream raw materials:

3-fluorophenol