<18O>acetophenone

Base Information

• Chemical Name: <18O>acetophenone
• CAS No.: 73007-56-4
• Molecular Formula: C₈H₈O
• Molecular Weight: 122.152
• Mol file: 73007-56-4.mol

Synonyms:<18O>acetophenone

Chemical Property of <18O>acetophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of <18O>acetophenone

There total 16 articles about <18O>acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

acetophenone dimethyl acetal (4316-35-2) → <18O>acetophenone (73007-56-4)

Guidance literature:

With sulfuric acid; ¹⁸O-labeled water; In tetrahydrofuran; water;

DOI:10.1021/ja00279a052

Reference yield:

ethylbenzene (100-41-4,27536-89-6) → styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + <18O>acetophenone (73007-56-4)

Guidance literature:

With CoO₄₀W₁₂^(5-)*16H₂O*5K⁽¹⁺⁾; lithium perchlorate; oxygen-18; In acetonitrile; at 25 ℃; for 3h; Electrochemical reaction;

DOI:10.1002/anie.201801372

Reference yield:

Isopropylbenzene (98-82-8) → 1-methyl-1-phenylethyl alcohol (617-94-7) + 2-phenylpropan-2-ol-18O + <18O>acetophenone (73007-56-4) + acetophenone (98-86-2)

Guidance literature:

With peracetic acid; C₂₀H₂₁N₄O₂Pd⁽¹⁺⁾*F₆P^(1-)*C₂H₃N; ¹⁸O-labeled water; 3-chloro-benzenecarboperoxoic acid; In acetonitrile; at 30 ℃; for 24h; Temperature; Inert atmosphere;

DOI:10.1002/cctc.202101345

upstream raw materials:

acetophenone dimethyl acetal

1,1,-diethoxy-1-phenylethane

1,1-diphenylethyl hydroperoxide

4-methyl-4-phenyl-1,2-dioxolane-3,5-dione

Downstream raw materials:

C₁₂H₁₉O₂⁽¹⁸⁾OPS

<18O>-1-phenyl-1-ethanol