Methyl 6-bromo-3-methoxy-2-nitrobenzoate

Base Information

Chemical Name:Methyl 6-bromo-3-methoxy-2-nitrobenzoate
CAS No.:127971-98-6
Molecular Formula:C₉H₈BrNO₅
Molecular Weight:290.07
Hs Code.:
DSSTox Substance ID:DTXSID701277423
Nikkaji Number:J329.352A

Synonyms:Methyl 6-bromo-3-methoxy-2-nitrobenzoate;127971-98-6;Benzoic acid, 6-bromo-3-methoxy-2-nitro-, methyl ester;SCHEMBL19890717;DTXSID701277423

Suppliers and Price of Methyl 6-bromo-3-methoxy-2-nitrobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
6-Bromo-3-methoxy-2-nitro-benzoicacidmethylester 95%
5 G
$ 1385.00

Chemcia Scientific
6-Bromo-3-methoxy-2-nitro-benzoicacidmethylester 95%
1 G
$ 395.00

Total 1 raw suppliers

Chemical Property of Methyl 6-bromo-3-methoxy-2-nitrobenzoate

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:288.95858
Heavy Atom Count:16
Complexity:280

Purity/Quality:: 6-Bromo-3-methoxy-2-nitro-benzoicacidmethylester 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)Br)C(=O)OC)[N+](=O)[O-]

Technology Process of Methyl 6-bromo-3-methoxy-2-nitrobenzoate

There total 3 articles about Methyl 6-bromo-3-methoxy-2-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 127971-97-5
6-bromo-3-methoxy-2-nitrobenzoic acid

: 127971-98-6
methyl 6-bromo-3-methoxy-2-nitrobenzoate

Guidance literature:: In diethyl ether; for 1h;
DOI:10.1021/jo00302a022

Reference yield: 84.0%

: 127971-97-5
6-bromo-3-methoxy-2-nitrobenzoic acid

: 74-88-4
methyl iodide

: 127971-98-6
methyl 6-bromo-3-methoxy-2-nitrobenzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 2h; Enzymatic reaction;

Reference yield:

: 4920-80-3
3-methoxy-2-nitrobenzoic acid

: 127971-98-6
methyl 6-bromo-3-methoxy-2-nitrobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / Br₂/Ag₂SO₄/H₂SO₄ / 2 h / Ambient temperature

2: 95 percent / diethyl ether / 1 h

With sulfuric acid; bromine; silver sulfate; In diethyl ether;
DOI:10.1021/jo00302a022