CID 15059973

Base Information

Chemical Name:CID 15059973
CAS No.:136904-70-6
Molecular Formula:C₃₀H₂₇N₅O₅S
Molecular Weight:569.641
Hs Code.:
DSSTox Substance ID:DTXSID601177119

Synonyms:

Suppliers and Price of CID 15059973

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of CID 15059973

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:569.17329015
Heavy Atom Count:41
Complexity:875

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2(C3=CC=CC=C3OC4=CC=CC=C42)SC5C(C(OC5N6C=NC7=C(N=CN=C76)N)CO)O
Isomeric SMILES:COC1=CC=C(C=C1)C2(C3=CC=CC=C3OC4=CC=CC=C42)S[C@@H]5[C@@H]([C@H](O[C@H]5N6C=NC7=C(N=CN=C76)N)CO)O

Technology Process of CID 15059973

There total 12 articles about CID 15059973 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 136904-73-9
2'deoxy-2'-<9-(4-methoxyphenyl)xanthen-9-yldithio>adenosine

: 136904-70-6
2'-S-<9-(4-methoxyphenyl)xanthen-9-yl>-2'-thioadenosine

Guidance literature:: With triphenylphosphine; In acetic acid; at 50 ℃; for 2h;
DOI:10.1016/0008-6215(92)84167-Q

Reference yield:

: 69304-45-6
3',5'-O-(1,1,3,3-tetra-isopropyldisiloxane-1,3-diyl)adenosine

: 136904-70-6
2'-S-<9-(4-methoxyphenyl)xanthen-9-yl>-2'-thioadenosine

Guidance literature:: Multi-step reaction with 5 steps

1: 1) CrO₃, pyridine, Ac₂O; 2) aq. NaBH₄ / 1) CH₂Cl₂, 9 min; 2) EtOH, 0 deg C, 30 min

2: 93 percent / pyridine / 16 h / Ambient temperature

3: 81 percent / pyridine / CH₂Cl₂ / 5 h / -15 - 10 °C

4: 1) Et₃N, 2) Et₄NF; 3) NH₃ / 1) DMSO, 32 h; 2) MeCN, room temp., 15 min; 3) MeOH, room temp., 22 h

5: 75 percent / PPh₃ / acetic acid / 2 h / 50 °C

With pyridine; chromium(VI) oxide; sodium tetrahydroborate; ammonia; acetic anhydride; tetraethylammonium fluoride; triethylamine; triphenylphosphine; In dichloromethane; acetic acid;
DOI:10.1016/0008-6215(92)84167-Q

Reference yield:

: 87792-02-7
9-[3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-1-β-D-arabinofuranosyl]adenine

: 136904-70-6
2'-S-<9-(4-methoxyphenyl)xanthen-9-yl>-2'-thioadenosine

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / pyridine / 16 h / Ambient temperature

2: 81 percent / pyridine / CH₂Cl₂ / 5 h / -15 - 10 °C

3: 1) Et₃N, 2) Et₄NF; 3) NH₃ / 1) DMSO, 32 h; 2) MeCN, room temp., 15 min; 3) MeOH, room temp., 22 h

4: 75 percent / PPh₃ / acetic acid / 2 h / 50 °C

With pyridine; ammonia; tetraethylammonium fluoride; triethylamine; triphenylphosphine; In dichloromethane; acetic acid;
DOI:10.1016/0008-6215(92)84167-Q