1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

Base Information

Chemical Name:1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one
CAS No.:1333127-93-7
Molecular Formula:C₁₂H₁₂N₂O
Molecular Weight:200.24
Hs Code.:

Synonyms:1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

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Chemical Property of 1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

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Technology Process of 1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

There total 5 articles about 1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 616-47-7
1-methyl-1H-imidazole

: 99-90-1
para-bromoacetophenone

: 1333127-93-7
1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

Guidance literature:: With C₂₄H₂₂ClN₃OPdSe; potassium carbonate; Trimethylacetic acid; In dimethyl amine; at 110 ℃; for 10h; Reagent/catalyst; regioselective reaction;
DOI:10.1021/acs.organomet.8b00246

Reference yield: 90.0%

: 1333127-93-7
1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

Guidance literature:: With C₃₀H₃₆B₁₀O₄P₂Pd; potassium carbonate; In methanol; at 20 ℃; for 6h;

Reference yield: 73.0%

: 616-47-7
1-methyl-1H-imidazole

: 99-91-2
para-chloroacetophenone

: 1333127-93-7
1-(4-(1-methyl-1H-imidazol-5-yl)phenyl)ethan-1-one

Guidance literature:: With C₄₈H₄₂Cl₄N₈O₂Pd₂; potassium carbonate; Trimethylacetic acid; In N,N-dimethyl acetamide; at 130 ℃; for 18h; regioselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1002/adsc.201901189