telmisartan tert-butylamine salt

Base Information

• Chemical Name: telmisartan tert-butylamine salt
• CAS No.: 862286-67-7
• Molecular Formula: C₄H₁₁N*C₃₃H₃₀N₄O₂
• Molecular Weight: 587.765
• Mol file: 862286-67-7.mol

Synonyms:telmisartan tert-butylamine salt

Chemical Property of telmisartan tert-butylamine salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of telmisartan tert-butylamine salt

There total 2 articles about telmisartan tert-butylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butylamine (75-64-9) + telmisatran (144701-48-4) → telmisartan tert-butylamine salt (862286-67-7)

Guidance literature:

In N,N-dimethyl-formamide;

Reference yield:

4'-[[2-n-propyl-4-methyl-6-(1-methyl-benzimidazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-2-cyano-biphenyl (144702-27-2) → telmisartan tert-butylamine salt (862286-67-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide; water / ethylene glycol / 18 h / 155 - 170 °C

1.2: 20 °C / pH 7

2.1: isopropyl alcohol / 3 h / Heating / reflux

With potassium hydroxide; water; In ethylene glycol; isopropyl alcohol;

upstream raw materials:

tert-butylamine

telmisatran

4'-[[2-n-propyl-4-methyl-6-(1-methyl-benzimidazol-2-yl)-1H-benzimidazol-1-yl]-methyl]-2-cyano-biphenyl

Refernces